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Anti-TLR4/MD-2 Complex Antibody (Biotin) LS-C10734

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Wt. Vol. Conc. Price
50 µg - - $515
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
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Rat Monoclonal (IgG2a) to Mouse TLR4/MD-2 Complex
Mouse
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Biotin Conjugated

Details

Mouse TLR4/MD-2 Complex
Rat
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Biotin
Purified

Applications

IHC - Frozen, Immunoprecipitation, Flow Cytometry (1:50)

Specificity and Use

Reacts with the Toll-like receptor 4 (TLR4, CD284). Reacts preferentially, especially in Flow Cytometry, with mouse TLR4 that is associated with MD-2. This antibody is a TLR4 function-blocking antibody that is useful for studies on the role of TLR4 as a receptor for LPS induced cytokine production by TLR4 bearing cells. The antibody was shown to coprecipitate MD-2 (30kD) with TLR4 (100kD). The antibody recognizes the mouse TLR4/MD-2 complex and is not useful for detection of TLR4 (CD284) alone.
Can be used for Flow Cytometry, Immunoprecipitation and Immunohistology on frozen sections. The antibody recognizes the mouse TLR4/MD-2 complex and is not useful for detection of TLR4 (CD284) alone. Immunohistology: 1:50. Flow Cytometry: 1:50.

Packaging

PBS, 0.02% sodium azide, 0.1% BSA.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C
For research use only.

About TLR4/MD-2 Complex


Requested From: United States
Date Requested: 9/28/2016

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