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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TLR4/MD‑2 Complex Antibody (Biotin) LS‑C10734
MD-2 Complex antibody LS-C10734 is a biotin-conjugated rat monoclonal antibody to mouse MD-2 Complex (TLR4). Validated for Flow, IHC and IP.
Antibody
Catalog
Size
Price
LS-C10734-50
50 µg
$605

Popular TLR4/MD-2 Complex Products

Antibody
Species: Human
Applications: Flow Cytometry
Cell surface flow cytometry of TLR4 in mouse peritoneal cells using antibody at 1 ug/1X10^6 cells. The green histogram represents the isotype control and red represents anti-TLR4 antibody.
Species: Mouse
Applications: Immunoprecipitation, Flow Cytometry
Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry, Functional Assay
Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry
Surface staining of thioglycollate induced PEC with anti-mouse Toll-like receptor 4/MD-2 (MTS510) PE. Appropriate isotype controls were used (open histogram). Cells in the large scatter population were used for analysis.
Species: Mouse
Applications: IHC, IHC - Frozen, Immunoprecipitation, Flow Cytometry

Product Description

MD-2 Complex antibody LS-C10734 is a biotin-conjugated rat monoclonal antibody to mouse MD-2 Complex (TLR4). Validated for Flow, IHC and IP.

Specifications

Target
Mouse TLR4/MD-2 Complex
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Biotin
Purification
Purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Immunoprecipitation
  • Flow Cytometry (1:50)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Specificity
Reacts with the Toll-like receptor 4 (TLR4, CD284). Reacts preferentially, especially in Flow Cytometry, with mouse TLR4 that is associated with MD-2. This antibody is a TLR4 function-blocking antibody that is useful for studies on the role of TLR4 as a receptor for LPS induced cytokine production by TLR4 bearing cells. The antibody was shown to coprecipitate MD-2 (30kD) with TLR4 (100kD). The antibody recognizes the mouse TLR4/MD-2 complex and is not useful for detection of TLR4 (CD284) alone.
Usage
Can be used for Flow Cytometry, Immunoprecipitation and Immunohistology on frozen sections. The antibody recognizes the mouse TLR4/MD-2 complex and is not useful for detection of TLR4 (CD284) alone. Immunohistology: 1:50. Flow Cytometry: 1:50. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.02% Sodium Azide, 0.1% BSA
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/21/2018

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