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Anti-TLR4 Antibody LS-C44226

Note: This antibody replaces LS-C57654, LS-C44222

Ordering

Wt. Vol. Conc. Price
100 µg - 1 mg/ml $250
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TLR4 Antibodies

Anti-TLR4 Antibody (Internal) IHC-plus™ LS-A9704
Rabbit Polyclonal to Human TLR4
Human
IHC - Paraffin
Unconjugated
Immunohistochemistry Image
Anti-TLR4 Antibody (aa100-200, clone 76B357.1) IHC-plus™ LS-B2070
Mouse Monoclonal [clone 76B357.1] (IgG2b,k) to Human TLR4
Human, Mouse, Rat
IHC - Paraffin, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image
Anti-TLR4 Antibody (clone HTA125, PE, Cy7) LS-C107190
Mouse Monoclonal [clone HTA125] (IgG2a,k) to Human TLR4
Human
Flow Cytometry
PE, Cy7 Conjugated
Flow Cytometry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgG2a) to Human TLR4
Human, Dog, Guinea pig, Pig, Rhesus monkey
Western blot, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Unconjugated

Details

Human TLR4
Mouse
Human, Dog, Guinea pig, Pig, Rhesus monkey (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Unconjugated. Also available conjugated with Biotin, FITC, RPE.
Protein G purified
Unmodified. Also available Low Endotoxin.

Applications

  • Western blot
  • Immunoprecipitation
  • Flow Cytometry (1:10 - 1:25)
  • (applications tested for the base form of this product only)

Specificity and Use

TLR4 antibody was raised against ba/F3 cell line expressing TLR4 (CD284).
Recognizes the human Toll like receptor 4 (TLR4) cell surface antigen. TLR4, also known as CD284, has been demonstrated to act as a receptor for LPS on human monocytes and macrophages. TLR4 signalling of LPS stimulation requires the presence of the MD-2 molecule. TLR4 is weakly expressed by resting cells, but is upregulated following stimulation with LPS. Has been demonstrated to block activation of monocytes with LPS. XXX recommend the use of MCA2061EL for this purpose.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells or 100 ul whole blood. Method sheets are available on request.

Packaging

PBS, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About TLR4

O00206 NM_138554 O00206

TLR4 Antibody, CD284 Antibody, CD284 antigen Antibody, Homolog of Drosophila toll Antibody, TLR-4 Antibody, TOLL Antibody, ARMD10 Antibody, Toll-like receptor 4 Antibody, HToll Antibody

Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific.

Requested From: United States
Date Requested: 12/4/2016

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