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Anti-TLR4 Antibody (Biotin) LS-C10716

Catalog Size Price
LS-C10716-100 100 µg Unavailable

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181 TLR4 Antibodies

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100% Guaranteed
Mouse Monoclonal (IgG2a) to Human TLR4
Human
Immunoprecipitation, Flow Cytometry, ELISA, Functional Assay
Biotin Conjugated

Details

Human TLR4
Mouse
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Biotin
Purified
Unmodified

Applications

  • Immunoprecipitation
  • Flow Cytometry
  • ELISA (1 µg/ml)
  • Functional Assay

Specificity and Use

TLR4 antibody was raised against ba/F3 cell line expressing human TLR4 cell surface antigen.
Recognizes human TLR4 (Toll Like Receptor 4) (Biotin).
ELISA, Flow cytometry. Functional studies: It has been shown to block the activation of monocytes with LPS). Immunoprecipitation: suitable. Recommended Dilution: ELISA: 1 ug/ml. Flow cytometry: 2-5 ug/1 x 10 cells. However, the optimal condition has to be determined for individual experiments. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Packaging

PBS, 0.02% sodium azide.
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
For research use only.

About TLR4

O00206 NM_138554 O00206

TLR4 Antibody, CD284 Antibody, CD284 antigen Antibody, Homolog of Drosophila toll Antibody, TLR-4 Antibody, TOLL Antibody, ARMD10 Antibody, Toll-like receptor 4 Antibody, HToll Antibody

Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific.

Requested From: 
Date Requested: 5/20/2018

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