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Anti-TLR4 Antibody (aa100-200) LS-C90573

Catalog Size Price
LS-C90573-100 100 µg (0.5 mg/ml) Unavailable

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100% Guaranteed
Mouse Monoclonal (IgG2b,k) to Human TLR4
Human, Mouse, Rat, Hamster
Western blot, Flow Cytometry
Unconjugated

Details

Human TLR4
Mouse
Human, Mouse, Rat, Hamster (tested or 100% immunogen sequence identity)
Bovine, Pig (at least 90% immunogen sequence identity)
IgG2b,k Monoclonal
Unconjugated
Protein G purified
Unmodified

Applications

  • Western blot
  • Flow Cytometry

Specificity and Use

TLR4 antibody was raised against this antibody was developed against a portion of amino acids 100-200 of human TLR4. Homology: 100% in Human, Chimp, Baboon, Chinese Hamster and Rat. 93% in Bovine and Porcine. 85% in Sheep. 78% in Cat, Horse and Mouse.
aa100-200
The amino acid sequence used is 100% homologous in human, chimp, baboon, Chinese hamster, and rat; 93% homologous in bovine and porcine; 85% homologous in sheep and 78% homologous in cat, horse and mouse. Species cross-reactivity: Cross-reacts with Human,
Suitable for use in Flow Cytometry and Western Blot.

Packaging

PBS, 0.05% BSA, 0.05% sodium azide.
Long term: Add glycerol (40-50%) -20°C; Short term: +4°C.
For research use only.

About TLR4

O00206 NM_138554 O00206

TLR4 Antibody, CD284 Antibody, CD284 antigen Antibody, Homolog of Drosophila toll Antibody, TLR-4 Antibody, TOLL Antibody, ARMD10 Antibody, Toll-like receptor 4 Antibody, HToll Antibody

Cooperates with LY96 and CD14 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MYD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Also involved in LPS-independent inflammatory responses triggered by free fatty acids, such as palmitate, and Ni2+. Responses triggered by Ni2+ require non-conserved histidines and are, therefore, species-specific.

Requested From: 
Date Requested: 8/21/2017

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