Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Western blot (1:10)
Flow Cytometry (1:10)
Recognizes human TLR3 (CD283).
Can be used for intracellular Flow Cytometry and Western Blot. Furthermore the antibody is useful for in vitro inhibition by the ligand poly (I): poly (C). Flow Cytometry: 1:10. Western Blot: 1:10. For inhibition studies dilutions have to be made according to the amounts ligand to be inactivated.
PBS, 0.1% BSA
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
TLR3 is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.