Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone 1030A5.138] (IgG1) to Human TLR2
IHC - Paraffin, Western blot, Flow Cytometry
Mouse Monoclonal (IgG2a) to Human TLR2
Western blot, Flow Cytometry
Human (tested or 100% immunogen sequence identity)
Western blot (1:50)
Flow Cytometry (1:50)
Specificity and Use
Specific for human TLR2 (CD282). Useful for studies on the role of TLR2 as a pattern recognition receptor in microbial products induced cytokine production by TLR2 bearing cells such as human peripheral blood mononuclear cells.
Can be used for Flow Cytometry, Western Blot and immunoassays. Flow Cytometry: 1:50. Western Blot: 1:50.
PBS, 0.02% sodium azide, 0.1% BSA.
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins.