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Anti-TLR2 Antibody LS-C10673

Ordering

Wt. Vol. Conc. Price
100 µg - 0.1 mg/ml $605
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Mouse Monoclonal (IgG2a) to Human TLR2
Human, Monkey
IHC - Paraffin, IHC - Frozen, Western blot, Immunoprecipitation, Flow Cytometry, Neutralization
Unconjugated

Details

Human TLR2
Mouse
Human, Monkey (tested or 100% immunogen sequence identity)
IgG2a Monoclonal
Protein G purified

Applications

IHC - Paraffin, IHC - Frozen, Western blot (1:25), Immunoprecipitation, Flow Cytometry (1:25), Neutralization

Specificity and Use

TLR2 antibody was raised against human Toll Like Receptor 2 (TLR2).
Recognizes human Toll-like receptor 2 (TLR2) at ~90kD. Species cross-reactivity: Cynomolgus monkey, rhesus monkey and marmoset monkey.
Suitable for use in Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Western Blot, Immunoassays and Neutralization of TLR2 (blocks TLR2 agonist-induced cellular activation). Flow Cytometry: 1:25. Immunohistochemistry (Frozen and Paraffin): 1:25. Western Blot: 1:25. Neutralization: In vitro dilutions have to be made according to the amount (s) of TLR2 to be inactivated. Before use in biological assays, the product must be filter sterilized and depending on the concentration to be used dialyzed against culture medium to remove the sodium azide added.

Packaging

PBS, 0.1% BSA.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About TLR2

O60603 NM_003264 NP_003255.2

TLR2 Antibody, CD282 antigen Antibody, CD282 Antibody, TIL4 Antibody, Toll-like receptor 2 Antibody

Cooperates with LY96 to mediate the innate immune response to bacterial lipoproteins and other microbial cell wall components. Cooperates with TLR1 or TLR6 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. May also promote apoptosis in response to lipoproteins.

Requested From: United States
Date Requested: 9/30/2016

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