Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, Immunofluorescence, Western blot, Flow Cytometry, ELISA
Mouse Monoclonal [clone TA205] (IgG1) to Human TLN1 / Talin 1
Human, Rabbit, Chicken
IHC - Frozen, Immunoprecipitation, Flow Cytometry
Human TLN1 / Talin 1
Human, Rabbit, Chicken (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [TA205]
Protein G purified
IHC - Frozen
Flow Cytometry (1:25 - 1:100)
Specificity and Use
TLN1 / Talin 1 antibody was raised against human platelet talin.
Western Blots the 225kD talin band on SDS gels of platelets and other cells. It may be used to stain adhesion plaques in fixed and permeabilized fibroblasts. TA205 recognizes an epitope within residues 139-433.
PBS, 0.09% sodium azide
+4°C or -20°C, Avoid repeated freezing and thawing.
TLN1 Antibody, KIAA1027 Antibody, TLN Antibody, Talin-1 Antibody, ILWEQ Antibody, Talin Antibody, Talin 1 Antibody
TLN1 / Talin is a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts. The encoded protein plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It codistributes with integrins in the cell surface membrane in order to assist in the attachment of adherent cells to extracellular matrices and of lymphocytes to other cells.