Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TLE2, ESG, Enhancer of split groucho 2, ESG2, GRG2
(tested or 100% immunogen sequence identity)
IHC - Frozen (1:200 - 1:1000)
ELISA (1:200 - 1:1000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
IHC - 4% paraformaldehyde
TLE2 antibody was raised against synthetic peptide from human Groucho 2 (aa 220-235, KEPSGPYESDEDKSDY) conjugated to BSA. Percent identity by BLAST analysis: Human (100%); Gorilla, Gibbon (94%); Elephant, Dog, Bovine, Horse (88%); Marmoset (81%).
Recognizes Groucho 2 / TLE2 / ESG2 transcription factor. Species cross-reactivity: Human and rodent.
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Immunohistochemistry (Frozen sections): 1:200-1:1000. Not tested for paraffin. Western Blot: 1:200-1:1000. ELISA: 1:200-1:1000.
PBS, pH 7.2, No preservatives added
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES.