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TJP3 / ZO3
tight junction protein 3
The protein encoded by this gene is a member of the membrane-associated guanylate kinase-like (MAGUK) protein family which is characterized by members having multiple PDZ domains, a single SH3 domain, and a single guanylate kinase-like (GUK)-domain. In addition, members of the zonula occludens protein subfamily have an acidic domain, a basic arginine-rich region, and a proline-rich domain. The protein encoded by this gene plays a role in the linkage between the actin cytoskeleton and tight-junctions and also sequesters cyclin D1 at tight junctions during mitosis. Alternative splicing results in multiple transcript variants encoding distinct isoforms. This gene has a partial pseudogene on chromosome 1.
| Gene Name: | tight junction protein 3 |
| Family/Subfamily: | Occludin , not assigned-Occludin |
| Synonyms: | TJP3, Tight junction protein 3, ZO-3, Zona occludens protein 3, Zonula occludens protein 3, Tight junction protein ZO-3, ZO3 |
| Target Sequences: | NM_014428 NP_055243.1 O95049 |
Publications (1)
1
A mouse model of human primitive neuroectodermal tumors resulting from microenvironmentally-driven malignant transformation of orthotopically transplanted radial glial cells. Malchenko S, Sredni ST, Hashimoto H, Kasai A, Nagayasu K, Xie J, Margaryan NV, Seiriki K, Lulla RR, Seftor RE, Pachman LM, Meltzer HY, Hendrix MJ, Soares MB. PloS one. 2015 10:e0121707. (ICC, IHC-P; Human)
[Full Text Article]
[PubMed:25826270]
[PMC:PMC4380339]
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(28)
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(28)
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(1)
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TJP3 / ZO3
(35)
Reactivity
Human
(27)
Mouse
(10)
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(9)
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(13)
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(2)
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(2)
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(27)
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(19)
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(12)
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(14)
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(1)
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rabbit
(28)
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(1)
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(22)
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(28)
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(3)
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(3)
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(3)
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(3)
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(3)
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(13)
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aa102-129
(7)
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(1)
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aa325-375
(1)
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(1)
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(1)
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(35)
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(1)
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(1)
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(1)
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(1)
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(2)
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(3)
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(4)
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(1)
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293T Cells
(1)
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(2)
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(2)
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(1)
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Purified
(2)
TJP3 / ZO3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Dog, Human
ELISA, IF, IHC, IHC-P, IP, WB
Unconjugated
50 µg/$485
TJP3 / ZO3 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, IP, WB
HRP Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, IP, WB
Biotin Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Human Polyclonal (FITC) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, IP, WB
FITC Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Human Polyclonal (APC) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, IP, WB
APC Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Dog, Rat, Human
ELISA, IF, IP, WB
PE Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Mouse Polyclonal (aa885-905) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TJP3 / ZO3 Rabbit anti-Human Polyclonal Antibody
Dog, Human
ELISA, IF, IP, WB
Unconjugated
100 µg/$786
TJP3 / ZO3 Rabbit anti-Human Polyclonal (HRP) Antibody
Dog, Human
ELISA, IF, IP, WB
HRP Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Human Polyclonal (Biotin) Antibody
Dog, Human
ELISA, IF, IP, WB
Biotin Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Human Polyclonal (FITC) Antibody
Dog, Human
ELISA, IF, IP, WB
FITC Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Human Polyclonal (APC) Antibody
Dog, Human
ELISA, IF, IP, WB
APC Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Human Polyclonal (PE) Antibody
Dog, Human
ELISA, IF, IP, WB
PE Conjugated
100 µl/$1,017
TJP3 / ZO3 Rabbit anti-Human Polyclonal (aa102-129) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
TJP3 / ZO3 Rabbit anti-Human Polyclonal (aa102-129) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
TJP3 / ZO3 Rabbit anti-Human Polyclonal (aa102-129) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
TJP3 / ZO3 Rabbit anti-Human Polyclonal (aa102-129) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
TJP3 / ZO3 Rabbit anti-Human Polyclonal (aa102-129) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
TJP3 / ZO3 Rabbit anti-Human Polyclonal (aa102-129) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
TJP3 / ZO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$357
TJP3 / ZO3 Rabbit anti-Human Polyclonal (aa883-933) Antibody
Human
IP, WB
Unconjugated
100 µl/$493
TJP3 / ZO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TJP3 / ZO3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
TJP3 / ZO3 Rabbit anti-Human Polyclonal (aa102-129) Antibody
Human
WB
Unconjugated
400 µl/$393
TJP3 / ZO3 Rabbit anti-Human Polyclonal (aa913-933) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
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