TIMP2

TIMP metallopeptidase inhibitor 2

TIMP2 is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.

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Products

Antibodies (127)

ELISA Kits (47)

Proteins (22)

Type

Cell-Based (1)

Custom (4)

Over-Expression Lysate (2)

Primary (127)

Recombinant (20)

Sandwich (39)

Sandwich CLIA (3)

Target

TIMP2 (196)

Reactivity

Human (98)

Mouse (57)

Rat (60)

Bat (3)

Bovine (28)

Canine (1)

Chicken (5)

Chimpanzee (6)

Cow (8)

Dog (20)

Equine (1)

Gibbon (9)

Guinea pig (16)

Hamster (4)

Horse (20)

Monkey (19)

Pig (18)

Porcine (1)

Rabbit (14)

Sheep (10)

Zebrafish (9)

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Application

IHC (27)

IHC-Fr (3)

IHC-P (23)

WB (117)

Flo (11)

ELISA (16)

ICC (3)

IF (22)

IP (4)

Peptide-ELISA (4)

Host

rabbit (95)

mouse (29)

goat (1)

sheep (2)

Product Group

IHCPlus (3)

PathPlus Cancer (3)

Isotype

IgG (23)

IgG1 (14)

IgG1,k (4)

IgG2a (3)

IgG2a,k (8)

Clonality

monoclonal mc (30)

polyclonal pc (95)

recombinant monoclonal rmc (2)

Clone

11C1081 (1)

1554CT494.262.47 (1)

1C3 (1)

3A4 (5)

5B11 (1)

5D7 (1)

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OTI1A6 (2)

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OTI1C4 (2)

OTI1D7 (2)

OTI2G7 (2)

OTI3G7 (2)

OTI3H8 (2)

SPM356 (2)

TIMP2/2044 (2)

TIMP2/2488R (2)

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12 x 8-Well Microstrips (3)

96-Well Microplate (14)

96-Well Strip Plate (29)

APC (6)

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Azide-free (4)

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Cy7 Conjugated (6)

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HRP Conjugated (11)

Magnetic beads Conjugated (1)

PE Conjugated (6)

Sepharose Conjugated (1)

Unconjugated (68)

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Epitope

aa27-220 (33)

C-Terminus (12)

aa2-88 (8)

aa33-153 (8)

aa130-179 (4)

aa40-89 (4)

N-Terminus, aa56-66 (2)

aa205-220 (2)

40-120 aa, Internal (1)

Ala47 (1)

Internal (1)

N-Terminus (1)

aa 30-220 (1)

aa178-193 (1)

aa179-190 (1)

aa21-70 (1)

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Publications

No (196)

Sample Type

Adherent Cell Cultures (1)

Cell Culture Supernatants (17)

Cell Lysates (6)

EDTA Plasma (2)

Heparin Plasma (2)

Plasma (37)

Saliva (2)

Serum (39)

Tissue Homogenates (15)

Tag

6His, C-terminus (4)

6His, N-terminus (1)

Fc (1)

GST (2)

His (6)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Bovine (1)

Dog (1)

Horse (1)

Human (14)

Mouse (3)

Rat (1)

Source

293T Cells (1)

CHO Cells (1)

E. coli (9)

HEK 293 Cells (4)

Human (1)

Human Cells (3)

Mammalian Cells (2)

Wheat Germ Extract (1)

Purification

Purified (6)

Low Endotoxin Level

Low endotoxin level (8)

Biologically Active

Biologically active (1)

Select

PathPlus™ TIMP2 Antibody (clone 5B11) LS-B5545

Cancer

(5.0) Rating

Antibody:

TIMP2 Mouse anti-Human Monoclonal (5B11) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

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PathPlus™ TIMP2 Antibody (clone F27P3A4) LS-B1660

Cancer

(5.0) Rating

Antibody:

TIMP2 Mouse anti-Human Monoclonal (F27P3A4) Antibody

Reactivity:

Chicken, Zebrafish, Pig, Horse, Rat, Hamster, Sheep, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$460

Select

IHC-plus™ TIMP2 Antibody (aa178-193) LS-B8328

(4.0) Rating

Antibody:

TIMP2 Mouse anti-Human Monoclonal (aa178-193) Antibody

Reactivity:

Rabbit, Mouse, Dog, Guinea pig, Sheep, Bovine, Rat, Hamster, Pig, Human, Monkey

Applications:

ELISA, IHC, IHC-Fr, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

Select

Mouse TIMP2 (Sandwich ELISA) ELISA Kit - LS-F55694

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$737

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Rat TIMP2 (Sandwich ELISA) ELISA Kit - LS-F2962

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, EDTA Plasma, Heparin Plasma, Serum

Price:

1 Plate/$795

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Human/Pig TIMP2 (Sandwich ELISA) ELISA Kit - LS-F3857

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human, Pig

Range:

28.67 - 7000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

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Mouse TIMP2 (Sandwich ELISA) ELISA Kit - LS-F5499

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$617

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TIMP2 Antibody (clone OTI1A6) LS-C173579

Antibody:

TIMP2 Mouse anti-Human Monoclonal (OTI1A6) Antibody

Reactivity:

Mouse, Dog, Rat, Human, Monkey

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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PathPlus™ TIMP2 Antibody (clone 3A4) LS-B4238

Cancer

(5.0) Rating

Antibody:

TIMP2 Mouse anti-Human Monoclonal (3A4) Antibody

Reactivity:

Chicken, Zebrafish, Pig, Rabbit, Mouse, Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$440

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Rat TIMP2 (Sandwich ELISA) ELISA Kit - LS-F39138

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$617

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Mouse TIMP2 (Sandwich ELISA) ELISA Kit - LS-F293

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.082 - 60 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

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IHC-plus™ TIMP2 Antibody (clone 1C3) LS-B5544

(4.0) Rating

Antibody:

TIMP2 Mouse anti-Human Monoclonal (1C3) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$505

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TIMP2 Antibody LS-C331538

Antibody:

TIMP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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TIMP2 Antibody (clone OTI1D7) LS-C173599

Antibody:

TIMP2 Mouse anti-Human Monoclonal (OTI1D7) Antibody

Reactivity:

Mouse, Dog, Rat, Human, Monkey

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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TIMP2 Antibody (clone OTI1B11) LS-C337581

Antibody:

TIMP2 Mouse anti-Human Monoclonal (OTI1B11) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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TIMP2 Antibody (Internal) LS-C352955

Antibody:

TIMP2 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Pig, Human, Monkey

Applications:

ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$299

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Human TIMP2 Protein (Recombinant His) (aa27-220) - LS-G11636

Source:

E. coli

Tag:

His

Molecular Weight:

23.3 kDa

Price:

10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,838

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Rat TIMP2 Protein (Recombinant 6His, N-terminus) (aa27-220) - LS-G11640

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

23.2 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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TIMP2 Antibody (N-Terminus, clone 3A4) LS-C95516

Antibody:

TIMP2 Mouse anti-Human Monoclonal (N-Terminus) (3A4) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Bovine, Rat, Pig, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

0.1 ml/$293; 0.5 ml/$538; 1 ml/$832

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TIMP2 Antibody (clone 1554CT494.262.47) LS-C392599

Antibody:

TIMP2 Mouse anti-Human Monoclonal (1554CT494.262.47) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

Select

TIMP2 Antibody (C-Terminus) LS-C145866

Antibody:

TIMP2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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TIMP2 Antibody (clone OTI2G7) LS-C173580

Antibody:

TIMP2 Mouse anti-Human Monoclonal (OTI2G7) Antibody

Reactivity:

Human

Applications:

Flo, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$434

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TIMP2 Antibody (aa27-220) LS-C296673

Antibody:

TIMP2 Rabbit anti-Mouse Polyclonal (aa27-220) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$281; 200 µl/$311; 500 µl/$412; 1 ml/$463; 2 ml/$563; 5 ml/$966

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TIMP2 Antibody (clone 11C1081) LS-C184138

Antibody:

TIMP2 Rabbit anti-Human Monoclonal (11C1081) Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$688

Select

TIMP2 Antibody LS-C752620

Antibody:

TIMP2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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