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Anti-TIMP2 Antibody LS-C10592

Ordering
Wt. Vol. Conc. Price
- 500 µl 0.2 mg/ml $530
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Mouse Monoclonal (IgG1) to Human TIMP2
Human
Western blot, Immunoprecipitation, ELISA
Unconjugated

Details

Human TIMP2
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal
Protein G purified

Applications

Western blot, Immunoprecipitation, ELISA

Specificity and Use

TIMP2 antibody was raised against native human pro-MMP-2/TIMP-2.
Recognizes a protein of 21kD, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2) and also reacts with the MMP-2/TIMP-2 complex. Reacts with human, does not react with mouse and rat.
ELISA (For coating, order without BSA). Immunoprecipitation (Use Protein G). (Ab 2 ug/mg protein lysate). Western Blot (Ab 1 ug/ml for 2hrs at RT). Cellular Localization: Cytoplasmic. Positive control: HFL-1 cells. Conditioned, serum-free medium from (TPA-treated) human fetal lung cells. Bladder, breast, and ovarian carcinomas.

Packaging

PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About TIMP2

P16035 NM_003255 NP_003246.1

TIMP2 Antibody, Metalloproteinase inhibitor 2 Antibody, TIMP-2 Antibody, CSC-21K Antibody

TIMP2 is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells.
(More About TIMP2)
Requested From: United States
Date Requested: 9/26/2016
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