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Anti-TIMP2 Antibody LS-C10592
Most Popular TIMP2 Antibodies
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Details
| Human TIMP2 | |
| Mouse | |
| Human (tested or 100% immunogen sequence identity) | |
| IgG1 Monoclonal | |
| Unconjugated | |
| Protein G purified | |
| Unmodified |
Applications
- Western blot
- Immunoprecipitation
- ELISA
Specificity and Use
| TIMP2 antibody was raised against native human pro-MMP-2/TIMP-2. | |
| Recognizes a protein of 21kD, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2) and also reacts with the MMP-2/TIMP-2 complex. Reacts with human, does not react with mouse and rat. | |
| ELISA (For coating, order without BSA). Immunoprecipitation (Use Protein G). (Ab 2 ug/mg protein lysate). Western Blot (Ab 1 ug/ml for 2hrs at RT). Cellular Localization: Cytoplasmic. Positive control: HFL-1 cells. Conditioned, serum-free medium from (TPA-treated) human fetal lung cells. Bladder, breast, and ovarian carcinomas. |
Packaging
| PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. | |
| Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles. | |
| For research use only. |
About TIMP2
P16035
NM_003255
NP_003246.1
TIMP2 Antibody, Metalloproteinase inhibitor 2 Antibody, TIMP-2 Antibody, CSC-21K Antibody
TIMP2 is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells.
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Date Requested: 4/19/2018
Date Requested: 4/19/2018
