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TIMP2 antibody LS-C10592 is an unconjugated mouse monoclonal antibody to human TIMP2. Validated for ELISA, IP and WB.
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Species:
Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Chicken, Zebrafish
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
Western blot, Immunoprecipitation
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat, Bovine, Guinea pig, Rabbit
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human, Monkey, Mouse, Rat, Dog
Applications:
IHC, IHC - Paraffin, Western blot, Flow Cytometry
Product Description
TIMP2 antibody LS-C10592 is an unconjugated mouse monoclonal antibody to human TIMP2. Validated for ELISA, IP and WB.
Specifications
Target
Human TIMP2
Synonyms
TIMP2, Metalloproteinase inhibitor 2, TIMP-2, CSC-21K
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
- Western blot
- Immunoprecipitation
- ELISA
Immunogen
TIMP2 antibody was raised against native human pro-MMP-2/TIMP-2.
Specificity
Recognizes a protein of 21kD, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2) and also reacts with the MMP-2/TIMP-2 complex. Reacts with human, does not react with mouse and rat.
Usage
ELISA (For coating, order without BSA). Immunoprecipitation (Use Protein G). (Ab 2 ug/mg protein lysate). Western Blot (Ab 1 ug/ml for 2hrs at RT). Cellular Localization: Cytoplasmic. Positive control: HFL-1 cells. Conditioned, serum-free medium from (TPA-treated) human fetal lung cells. Bladder, breast, and ovarian carcinomas.
Presentation
PBS, pH 7.4, 0.09% Sodium Azide, 0.2% BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About TIMP2
TIMP2 is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells.
P16035
NM_003255
NP_003246.1
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Requested From: United States
Date Requested: 10/19/2018
Date Requested: 10/19/2018
