TIMP1

TIMP metallopeptidase inhibitor 1

Metalloproteinase inhibitor that functions by forming one to one complexes with target metalloproteinases, such as collagenases, and irreversibly inactivates them by binding to their catalytic zinc cofactor. Acts on MMP1, MMP2, MMP3, MMP7, MMP8, MMP9, MMP10, MMP11, MMP12, MMP13 and MMP16. Does not act on MMP14. Also functions as a growth factor that regulates cell differentiation, migration and cell death and activates cellular signaling cascades via CD63 and ITGB1. Plays a role in integrin signaling. Mediates erythropoiesis in vitro; but, unlike IL3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors.

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Products

Antibodies (167)

ELISA Kits (64)

Proteins (32)

Type

Competitive EIA (1)

Custom (4)

Development Kit (3)

Over-Expression Lysate (2)

Primary (167)

Recombinant (29)

Sandwich (49)

Sandwich CLIA (7)

Target

TIMP1 (263)

Reactivity

Human (123)

Mouse (34)

Rat (52)

Bovine (13)

Chicken (1)

Dog (10)

Ferret (1)

Guinea pig (2)

Horse (15)

Macaque (1)

Monkey (3)

Pig (4)

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IHC (38)

IHC-Fr (1)

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WB (144)

Flo (3)

ELISA (60)

ICC (15)

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IHC-Pfa (1)

IP (11)

Peptide-ELISA (2)

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rabbit (102)

mouse (61)

goat (1)

guinea pig (3)

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DevKit Core (2)

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IHCPlus (2)

Isotype

IgG (58)

IgG1 (14)

IgG1,k (14)

IgG2a (1)

IgG2a,k (8)

Clonality

monoclonal mc (62)

polyclonal pc (105)

Clone

009 (1)

12 (1)

2A5 (2)

3F10F14 (5)

4D12 (1)

6 (1)

7-6C1 (1)

ABT-TIMP1 (1)

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1000 Wells (1)

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Antibody Pair and Standard (1)

APC (9)

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Azide-free (1)

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Epitope

aa25-207 (18)

aa24-217 (16)

aa24-178 (8)

aa24-197 (8)

aa32-207 (8)

aa35-160 (8)

aa189-207 (4)

aa24-207 (4)

aa59-108 (4)

Cys24-Ala207 (2)

30-110 aa, Internal (1)

C-Terminus (1)

Internal (1)

aa129-143 (1)

aa157-188 (1)

aa41-70 (1)

aa61-110 (1)

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Publications

No (260)

Yes (3)

Sample Type

Cell Culture Supernatants (23)

Cell Lysates (11)

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Plasma (53)

Saliva (2)

Serum (54)

Tissue Homogenates (25)

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6His, C-terminus (2)

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GST (1)

GST, N-terminus + His, C-terminus (1)

His (12)

His, N-terminus (1)

His-GST (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Dog (1)

Horse (1)

Human (15)

Mouse (8)

Rabbit (1)

Rat (4)

Sheep (1)

Source

293T Cells (1)

E. coli (17)

HEK 293 Cells (3)

Human Cells (6)

Insect Cells (1)

Mammalian Cells (2)

Wheat Germ Extract (1)

Purification

Purified (11)

Low Endotoxin Level

Low endotoxin level (16)

Biologically Active

Biologically active (2)

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TIMP1 Antibody LS-C39715

Antibody:

TIMP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rabbit, Sheep, Bovine, Rat, Horse, Ferret, Human

Applications:

ELISA, IHC, IHC-Pfa, WB

Format:

Unconjugated

Price:

100 µg/$984

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IHC-plus™ TIMP1 Antibody (aa24-207) LS-B7485

(4.0) Rating

Antibody:

TIMP1 Rabbit anti-Human Polyclonal (aa24-207) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$485

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Rabbit TIMP1 (Sandwich ELISA) ELISA Kit - LS-F56296

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

15.625 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

TIMP1 Antibody (Preservative Free) LS-C149170

Antibody:

TIMP1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated, Preservative Free

Price:

20 µg/$242; 100 µg/$304; 200 µg/$334; 500 µg/$452

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Mouse TIMP1 (Sandwich ELISA) ELISA Kit - LS-F10062

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$782

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Human TIMP1 (Sandwich ELISA) ELISA Kit - LS-F195

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

24.69 - 18000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$588

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IHC-plus™ TIMP1 Antibody (aa157-188) LS-B10535

(4.0) Rating

Antibody:

TIMP1 Rabbit anti-Human Polyclonal (aa157-188) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$460

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TIMP1 Antibody (clone F31P2A5) LS-C41071

Antibody:

TIMP1 Mouse anti-Human Monoclonal (F31P2A5) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$359

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Mouse TIMP1 (Sandwich ELISA) ELISA Kit - LS-F10482

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$795

Select

Dog TIMP1 (Sandwich ELISA) ELISA Kit - LS-F6887

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Dog

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$854

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TIMP1 Antibody (clone 4D12) LS-C198343

Antibody:

TIMP1 Mouse anti-Human Monoclonal (4D12) Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$423

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TIMP1 Antibody (aa189-207) LS-C172306

Antibody:

TIMP1 Rabbit anti-Human Polyclonal (aa189-207) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$380

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TIMP1 Antibody (Internal) LS-C368646

Antibody:

TIMP1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

Flo, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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TIMP1 Antibody (aa35-160) LS-C296668

Antibody:

TIMP1 Rabbit anti-Mouse Polyclonal (aa35-160) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$276; 200 µl/$304; 500 µl/$398; 1 ml/$445; 2 ml/$538; 5 ml/$913

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TIMP1 Antibody (aa35-160, Biotin) LS-C299465

(4.0) Rating

(1) Publication(s)

Antibody:

TIMP1 Rabbit anti-Mouse Polyclonal (aa35-160) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$283; 200 µl/$313; 500 µl/$417; 1 ml/$468; 2 ml/$571; 5 ml/$981

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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TIMP1 Antibody (clone 3F10F14) LS-C319215

Antibody:

TIMP1 Mouse anti-Human Monoclonal (3F10F14) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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Porcine TIMP1 (Sandwich ELISA) ELISA Kit - LS-F56164

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Human TIMP1 (Sandwich ELISA) ELISA Kit - LS-F2553

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Saliva, Serum

Price:

1 Plate/$795

Select

Rat TIMP1 (Sandwich ELISA) ELISA Kit - LS-F5602

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$610

Select

TIMP1 Antibody LS-C11473

Antibody:

TIMP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.1 mg/$1,276

Select

TIMP1 Antibody (clone 2A5) LS-C27033

Antibody:

TIMP1 Mouse anti-Human Monoclonal (2A5) Antibody

Reactivity:

Human, Macaque

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µg/$466

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TIMP1 Antibody LS-C188023

Antibody:

TIMP1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC-P, WB

Format:

Unconjugated

Price:

0.1 mg/$579

Select

TIMP1 Antibody LS-C285818

Antibody:

TIMP1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$316; 100 µg/$386

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TIMP1 Antibody LS-C212354

Antibody:

TIMP1 Mouse anti-Rat Monoclonal Antibody

Reactivity:

Rat

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$316; 100 µg/$386

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TIMP1 Antibody (aa41-70) LS-C161891

Antibody:

TIMP1 Rabbit anti-Human Polyclonal (aa41-70) Antibody

Reactivity:

Human

Applications:

Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

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