Human TIMP1

Mouse

Human (tested or 100% immunogen sequence identity)

Rabbit

IgG1 Monoclonal

T2

Unconjugated

Protein A purified

Unmodified

Human TIMP-1.

Recognizes human Metalloproteinase inhibitor 1, also known as TIMP-1, Erythroid-potentiating activity, Fibroblast collagenase inhibitor or Tissue inhibitor of metalloproteinases 1. TIMP-1 is a 207 amino acid ~28 kD secreted metalloproteinase inhibitor. Reacting with both the reduced and non-reduced forms of TIMP-1. TIMP-1 is expressed by a wide range of cells including microvascular endothelial cells, smooth muscle cells, mesangial cells and some fibroblasts. TIMP-1 inhibits matrix metalloproteinase activity by forming complexes via reversible non covalent binding. It is reported to be involved in the control of angiogenesis and tumor growth. Has been shown to inhibit biological activity.

• Western blot (1:100 - 1:400)
• ELISA (1:100 - 1:400)

PBS, 0.09% Sodium Azide

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

This antibody carries the LSBio 100% Guarantee.

Uniprot: P01033 NCBI: NM_003254 NP_003245.1