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Anti-TIMELESS Antibody (N-Terminus) LS-C10582

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Wt. Vol. Conc. Price
- 100 µl - $605
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Rabbit Polyclonal (IgG) to Human TIMELESS
Human, Mouse
Western blot, ELISA
Unconjugated

Details

Human TIMELESS
Rabbit
Human, Mouse (tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
IgG Polyclonal
Antiserum

Applications

Western blot (1:1000 - 1:5000), ELISA (1:10000 - 1:100000)

Specificity and Use

TIMELESS antibody was raised against synthetic peptide including both a 14 aa peptide sequence near the N-terminus of mouse TIM1 and 14 aa peptide sequence from the C-terminus of human TIM1 (KLH).
N-Terminus
Recognizes both mouse and human Tim1. Species sequence homology: (mouse) rat 100%, drosophila and human TIM1 85% (human) mouse 57%.
Suitable for use in ELISA, Western Blot. Western Blot: 1:1000-1:5000. ELISA: 1:10000-1:100000 using 50-100 ng of control peptide/well.

Packaging

0.05% sodium azide, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About TIMELESS

Q9UNS1 NM_003920 NP_003911.2

TIMELESS Antibody, Timeless (Drosophila) homolog Antibody, Timeless circadian clock Antibody, TIMELESS1 Antibody, TIM1 Antibody, Protein timeless homolog Antibody, HTIM Antibody, TIM Antibody, Timeless homolog (Drosophila) Antibody, Tof1 homolog Antibody

Plays an important role in the control of DNA replication, maintenance of replication fork stability, maintenance of genome stability throughout normal DNA replication and in the regulation of the circadian clock. Involved in the determination of period length and in the DNA damage-dependent phase advancing of the circadian clock. Negatively regulates CLOCK|NPAS2-ARTNL/BMAL1|ARTNL2/BMAL2-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus.

Requested From: United States
Date Requested: 9/24/2016

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