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Anti-TICAM2 / TRAM Antibody (C-Terminus) IHC-plus™ LS-B713

Note: This antibody replaces LS-C26887

Ordering

Wt. Vol. Conc. Price
50 µg - - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TICAM2 / TRAM Antibodies

Anti-TICAM2 / TRAM Antibody (C-Terminus) LS-C344
Rabbit Polyclonal to Human TICAM2 / TRAM
Human
ICC, Western blot
Unconjugated
Immunocytochemistry Image
Anti-TICAM2 / TRAM Antibody (C-Terminus) LS-C363
Rabbit Polyclonal to Human TICAM2 / TRAM
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
Immunohistochemistry Image
Anti-TICAM2 / TRAM Antibody (C-Terminus) IHC-plus™ LS-B713
Rabbit Polyclonal to Human TICAM2 / TRAM
Human
IHC - Paraffin, Western blot
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human TICAM2 / TRAM
Human
IHC - Paraffin, Western blot
Unconjugated

Details

Human TICAM2 / TRAM
Rabbit
Human (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin (10 µg/ml)
  • Western blot

Specificity and Use

C-Terminus
Peptide corresponding to amino acids at the C terminus of human TIRP
Immunohistochemistry: LS-B713 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B713 was determined to be 10 ug/ml.

Packaging

PBS, 0.02% sodium azide.
+4°C or -20°C, Avoid repeated freezing and thawing.
For research use only.

About TICAM2 / TRAM

Q86XR7 NM_021649 NP_067681.1

TICAM2 Antibody, Cytoplasmic adaptor Antibody, TRIF-related adapter molecule Antibody, TIRAP3 Antibody, TRIF-related adaptor molecule Antibody, TICAM-2 Antibody, TIRP Antibody, TRAM Antibody

Functions as sorting adapter in LPS-TLR4 signaling to regulate the MYD88-independent pathway during the innate immune response to LPS. Physically bridges TLR4 and TICAM1 and functionally transmits LPS-TRL4 signal to TICAM1; signaling is proposed to occur in early endosomes after endocytosis of TLR4. May also be involved in IL1-triggered NF-kappa-B activation, functioning upstream of IRAK1, IRAK2, TRAF6, and IKBKB; however, reports are controversial.

Immunohistochemistry

Immunohistochemistry
Anti-TICAM2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B713 concentration 10 ug/ml.

Western blot

Western blot
Western blot of TIRP in PC-3 cell lysate with TIRP antibody at 1 g/ml.

Requested From: United States
Date Requested: 12/5/2016

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