Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone TSH-116] (IgG2a) to Human Thyrotropin / TSH
Human Thyrotropin / TSH
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [TSH-116]
Radioimmunoassay (1:100 - 1:2000)
Specificity and Use
Full length native protein (purified) (Human).
This antibody (clone TSH-116) reacts with human thyroid stimulating hormone (hTSH, thyrotropin), a glycoprotein hormone produced by the anterior pituitary gland cells in response to signals from the hypothalamus gland in the brain. The TSH-116 reacts with association constant 1.1 x 1011 l/mol. Following cross-reactivity expressed as binding of labeled hormone (% of total) was determined by solid phase RIA with excess of the antibody TSH-116: hTSH (78.9), hCG (20.3), hLH (23.2), hFSH (29.9).
PBS, pH 7.4, 15 mM sodium azide.
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.