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Anti-THRA / THR Alpha Antibody (Ligand-binding Domain) IHC-plus™ LS-A6194

Note: This antibody replaces LS-C42456
Catalog Size Price
LS-A6194-50 50 µg (1 mg/ml) Unavailable
Same day shipping In Stock - Same day shipping

Most Popular THRA / THR Alpha Antibodies

Anti-THRA / THR Alpha Antibody (Ligand-binding Domain) IHC-plus™ LS-A6196
Rabbit Polyclonal to Human THRA / THR Alpha
Human, Monkey
IHC, IHC - Paraffin
Unconjugated
Anti-THRA antibody LS-A6196 IHC of human surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-THRA / THR Alpha Antibody (aa147-158) IHC-plus™ LS-B4351
Goat Polyclonal to Human THRA / THR Alpha
Human, Monkey, Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Sheep
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Unconjugated
Anti-THRA antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4351 concentration 3.75 ug/ml.
Anti-THRA / THR Alpha Antibody (aa325-374) LS-C134993
Rabbit Polyclonal to Rat THRA / THR Alpha
Rat, Human, Monkey, Mouse, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit, Sheep, Zebrafish
Western blot
Unconjugated
THRA antibody LS-C134993 Western blot of Rat Muscle lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Anti-THRA / THR Alpha Antibody (aa10-90) LS-C386528
Rabbit Polyclonal (IgG) to Human THRA / THR Alpha
Human, Mouse, Rat
IHC, Western blot, ELISA
Unconjugated
Anti-THRA / THR Alpha Antibody (aa1-490, Biotin) LS-C686891
Rabbit Polyclonal (IgG) to Human THRA / THR Alpha
Human
IHC, Western blot
Biotin Conjugated
Western blot of THRA / THR Alpha antibody.

100% Guaranteed In Stock
Rabbit Polyclonal to Human THRA / THR Alpha
Human, Monkey
IHC, IHC - Paraffin
Unconjugated

Details

Human THRA / THR Alpha
Rabbit
Human, Monkey (tested or 100% immunogen sequence identity)
Mouse, Rat, Bovine, Dog, Hamster, Horse, Pig, Rabbit, Sheep (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC
  • IHC - Paraffin (10 - 15 µg/ml)

Specificity and Use

Synthetic 20 amino acid peptide from ligand-binding domain of human THRA. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Mouse, Rat, Sheep, Dog, Bovine, Hamster, Elephant, Panda, Rabbit, Horse, Pig (95%); Lizard (85%); Opossum (80%).
LS-E29114 - Liquid - 50 µg - $145.00
Immunizing peptide used to generate LS-A6194. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Ligand-binding Domain
Human THRA. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Immunohistochemistry: LS-A6194 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-A6194 was determined to be 10 ug/ml.

Packaging

PBS, less than 0.1% sodium azide.
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
For research use only.

About THRA / THR Alpha

P10827 NM_003250 NP_003241.2

THRA Antibody, AR7 Antibody, C-ERBA-1 Antibody, C-erbaalpha Antibody, EAR-7.1/EAR-7.2 Antibody, ERB-T-1 Antibody, ERBA1 Antibody, EAR-7 Antibody, ERBA-related 7 Antibody, HTR alpha 1 Antibody, HTR alpha 2 Antibody, THRA1 Antibody, Thyroid hormone receptor alpha Antibody, T3R Antibody, Tralpha2 Antibody, Triiodothyronine receptor Antibody, V-erbA-related protein 7 Antibody, Thyroid hormone receptor Antibody, Tralpha1 Antibody, NR1A1 Antibody, THRA3 Antibody, C-erbA-alpha Antibody, CHNG6 Antibody, EAR7 Antibody, ERBA Antibody, Erba-alpha Antibody, THRA2 Antibody, TR alpha Antibody, Tralpha Antibody

Thyroid hormone receptor alpha (TR alpha), a NR1 Thyroid Hormone-Like Receptor, mediates the diverse actions of thyroid hormone in development, differentiation, and metabolism. Four protein isoforms are encoded by the same TR alpha genomic locus: TR alpha1 (410 aa) (Nakai et al. 1988), TR alpha2 (490 aa) ( Nakai et al. 1988), TR deltaalpha1 (~154 aa), and TR deltaalpha2 (~237 aa); however, only TR alpha1 is able to bind the ligand ( Lazar et al. 1988).

Immunohistochemistry

Anti-THRA antibody LS-A6194 IHC of human surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-THRA antibody LS-A6194 IHC of human surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Requested From: 
Date Requested: 5/24/2018

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