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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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THBD / CD141 / Thrombomodulin Antibody LS‑C125315
Antibody
Thrombomodulin antibody LS-C125315 is an unconjugated rat monoclonal antibody to human Thrombomodulin (THBD / CD141). Validated for Flow, Func and WB.
Catalog
Size
Price
LS-C125315-100
100 µg (0.1 mg/ml)
Unavailable

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Product Description

Thrombomodulin antibody LS-C125315 is an unconjugated rat monoclonal antibody to human Thrombomodulin (THBD / CD141). Validated for Flow, Func and WB.
About THBD / CD141 / Thrombomodulin
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. P07204 NM_000361 NP_000352.1

THBD Antibody, BDCA3 Antibody, CD141 antigen Antibody, CD141 Antibody, AHUS6 Antibody, Fetomodulin Antibody, THPH12 Antibody, TM Antibody, THRM Antibody, Thrombomodulin Antibody


Specifications

Target
Human THBD / CD141 / Thrombomodulin
Host
Rat
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Applications
  • Western blot (1:10)
  • Flow Cytometry (1:10)
  • Functional Assay
Immunogen
Human CD141.
Specificity
Recognizes human thrombomodulin. Reacts with the EGF4 domain, thereby inhibiting the biological activity of thrombomodulin.
Usage
Suitable for use in Flow Cytometry, Western Blot, and inhibition of biological activity of thrombomodulin. Flow Cytometry: 1:10. Western Blot: 1:10.
Presentation
PBS, 0.1% BSA
Storage
May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/19/2018

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