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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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THBD / CD141 / Thrombomodulin Antibody (clone QBEND/40) LS‑C11657
Note: This antibody replaces LS-C45264
Thrombomodulin antibody LS-C11657 is an unconjugated mouse monoclonal antibody to Thrombomodulin (THBD / CD141) from human and rabbit. Validated for Flow and IHC.
Antibody
Catalog
Size
Price
LS-C11657-1000
1000 µl
$405

Popular THBD / CD141 / Thrombomodulin Products

Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, ICC, Western blot, Flow Cytometry, ELISA
Anti-CD141 / Thrombomodulin antibody IHC of human placenta, trophoblast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8509 dilution 1:50.
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Antibody
Species: Human
Applications: Western blot, Flow Cytometry, Functional Assay

Product Description

Thrombomodulin antibody LS-C11657 is an unconjugated mouse monoclonal antibody to Thrombomodulin (THBD / CD141) from human and rabbit. Validated for Flow and IHC.
About THBD / CD141 / Thrombomodulin
Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. P07204 NM_000361 NP_000352.1

THBD Antibody, BDCA3 Antibody, CD141 antigen Antibody, CD141 Antibody, AHUS6 Antibody, Fetomodulin Antibody, THPH12 Antibody, TM Antibody, THRM Antibody, Thrombomodulin Antibody


Specifications

Target
Human THBD / CD141 / Thrombomodulin
Host
Mouse
Reactivity
Human, Rabbit (tested or 100% immunogen sequence identity)
Clonality
IgG2a Monoclonal [QBEND/40]
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:10 - 1:50)
  • IHC - Frozen (1:10 - 1:100)
  • Flow Cytometry (1:1)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Human endothelium (thrombomodulin).
Specificity
Recognizes all human endothelium tested. Preliminary evidence suggests that Recognizes Thrombomodulin, but does not inhibit Thrombomodulin dependent activation of protein C.
Usage
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100ul. Immunohistochemistry: This product requires antigen retrieval using heat treatment methods prior to staining of paraffin sections. Sodium Citrate pH6.0 is recommended for this purpose. Histology Positive Control Tissue: Lymph node.
Presentation
Tissue Culture Supernatant, 0.01% Sodium Azide
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/18/2018

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