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TH / Tyrosine Hydroxylase
tyrosine hydroxylase
Tyrosine hydroxylase in involved in the conversion of phenylalanine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines and as such has a key role in the physiology of adrenergic neurons. TH is encoded by four distinct mRNAs produced by alternative splicing of a single primary transcript. Expression of the mRNAs varies in different parts of the nervous system. Defects in TH are the cause of autosomal recessive Segawa syndrome.
| Gene Name: | tyrosine hydroxylase |
| Family/Subfamily: | Monooxygenase |
| Synonyms: | TH, DYT14, Dystonia 14, TYH, Tyrosine 3-hydroxylase, Tyrosine hydroxylase, DYT5b, Tyrosine 3-monooxygenase |
| Target Sequences: | NM_000360 NP_000351.2 P07101 |
Publications (6)
1
Chronic Sleep Disruption Advances the Temporal Progression of Tauopathy in P301S Mutant Mice. Zhu Y, Zhan G, Fenik P, Brandes M, Bell P, Francois N, Shulman K, Veasey S. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2018 November;38:10255-10270. [Full Text Article]
[PubMed:30322903]
[PMC:PMC6262148]
Related Antibodies: LS-C124752.
2
Dorsomedial hypothalamic NPY affects cholecystokinin-induced satiety via modulation of brain stem catecholamine neuronal signaling. de La Serre CB, Kim YJ, Moran TH, Bi S. American journal of physiology. Regulatory, integrative and comparative physiology. 2016 November;311:R930-R939. [Full Text Article]
[PubMed:27534875]
[PMC:PMC5130582]
Related Antibodies: LS-C85507.
3
Single-Cell RNA-seq Reveals Profound Alterations in Mechanosensitive Dorsal Root Ganglion Neurons with Vitamin E Deficiency. Finno CJ, Peterson J, Kang M, Park S, Bordbari MH, Durbin-Johnson B, Settles M, Perez-Flores MC, Lee JH, Yamoah EN. iScience. 2019 November;21:720-735. [Full Text Article]
[PubMed:31733517]
[PMC:PMC6864320]
Related Antibodies: LS-C354112.
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TH / Tyrosine Hydroxylase Mouse anti-Human Monoclonal (1D8) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Neuroscience
TH / Tyrosine Hydroxylase Rabbit anti-Rat Polyclonal (pSer40) Antibody
Rat, Human
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µl/$460
Neuroscience
TH / Tyrosine Hydroxylase Rabbit anti-Rat Polyclonal Antibody
Mouse, Rat, Cat, Ferret, Human
ELISA, IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$485
TH / Tyrosine Hydroxylase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Dog, Bovine, Rat, Human
ICC, IF, IHC, IHC-P, IP, WB
Unconjugated
100 µl/$299
TH / Tyrosine Hydroxylase Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Chicken, Mouse, Dog, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
Competitive EIA
96-Well Strip Plate
Dog
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$929
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$798
TH / Tyrosine Hydroxylase Rabbit anti-Human Polyclonal (aa41-90) Antibody
Mouse, Rat, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Neuroscience
TH / Tyrosine Hydroxylase Rabbit anti-Rat Polyclonal Antibody
Rat, Human
IF, IHC, IHC-Fr, IHC-P, WB
Unconjugated
50 µl/$440
TH / Tyrosine Hydroxylase Mouse anti-Mouse Monoclonal (C-Terminus) (185) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
1 ml/$3,501
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TH / Tyrosine Hydroxylase Mouse anti-Rat Monoclonal Antibody
Rabbit, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$564
TH / Tyrosine Hydroxylase Chicken anti-Mouse Polyclonal Antibody
Mouse
ICC, IHC, WB
Unconjugated
200 µg/$924
TH / Tyrosine Hydroxylase Rabbit anti-Drosophila Polyclonal (N-Terminus) Antibody
Drosophila
ELISA, WB
Unconjugated
50 µg/$440; 100 µg/$480
TH / Tyrosine Hydroxylase Rabbit anti-Human Polyclonal (aa63-78) Antibody
Rat, Human
IHC
Unconjugated
100 µl/$688
Neuroscience
TH / Tyrosine Hydroxylase Mouse anti-Human Monoclonal (OTI3H3) Antibody
Mouse, Human
IF, IHC-P, WB
Unconjugated
50 µl/$460
TH / Tyrosine Hydroxylase Sheep anti-Rat Polyclonal Antibody
Rat, Human
IF, IHC, IHC-Fr, WB
Unconjugated
100 µl/$469
TH / Tyrosine Hydroxylase Mouse anti-Rat Monoclonal (TH-100) Antibody
Rabbit, Rat, Human
IHC, IHC-Fr, IHC-P, WB
Unconjugated
100 µg/$380
TH / Tyrosine Hydroxylase Mouse anti-Rat Monoclonal Antibody
Chicken, Bovine, Rat
IHC, WB
Unconjugated
40 µg/$839
TH / Tyrosine Hydroxylase Rabbit anti-Human Polyclonal (p19) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
TH / Tyrosine Hydroxylase Rabbit anti-Human Polyclonal (pSer40) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TH / Tyrosine Hydroxylase Mouse anti-Rat Monoclonal (TS106) Antibody
Rat
ELISA, ICC, IF, IHC
Unconjugated
250 µl/$816
TH / Tyrosine Hydroxylase Rabbit anti-Human Polyclonal (aa82-310) (FITC) Antibody
Mouse, Rat, Human
WB
FITC Conjugated
100 µl/$341; 200 µl/$397; 500 µl/$583; 1 ml/$715; 2 ml/$953; 5 ml/$1,628
TH / Tyrosine Hydroxylase Rabbit anti-Human Polyclonal (aa82-310) (APC, Cy7) Antibody
Mouse, Rat, Human
WB
APC, Cy7 Conjugated
100 µl/$489; 200 µl/$614; 500 µl/$1,108; 1 ml/$1,329; 2 ml/$1,860; 5 ml/$3,487
Sandwich
96-Well Strip Plate
Mouse
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$854
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