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Anti-TH / Tyrosine Hydroxylase Antibody (C-Terminus) LS-C40060

Ordering

Wt. Vol. Conc. Price
- 50 µl - $415
- 100 µl - $620
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular TH / Tyrosine Hydroxylase Antibodies

Anti-TH / Tyrosine Hydroxylase Antibody IHC-plus™ LS-B3443
Rabbit Polyclonal (IgG) to Rat TH / Tyrosine Hydroxylase
Rat, Human, Mouse, Cat, Ferret
IHC - Paraffin, IHC - Frozen, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Unconjugated
Immunohistochemistry Image
Anti-TH / Tyrosine Hydroxylase Antibody (N-Terminus) LS-C153588
Rabbit Polyclonal to Drosophila TH / Tyrosine Hydroxylase
Drosophila
Western blot, ELISA
Unconjugated
Anti-TH / Tyrosine Hydroxylase Antibody (C-Terminus, clone EP1532Y) IHC-plus™ LS-B8480
Rabbit Monoclonal [clone EP1532Y] (IgG) to Human TH / Tyrosine Hydroxylase
Human, Mouse, Rat
IHC - Paraffin, ICC, Western blot, Flow Cytometry
Unconjugated
Immunohistochemistry Image

100% Guaranteed 100% Guaranteed
Mouse Monoclonal (IgM) to Rat TH / Tyrosine Hydroxylase
Rat, Human, Monkey, Mouse
IHC - Frozen, Western blot
Unconjugated

Details

Rat TH / Tyrosine Hydroxylase
Mouse
Rat, Human, Monkey, Mouse (tested or 100% immunogen sequence identity)
IgM Monoclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • IHC - Frozen
  • Western blot (1:1000 - 1:2000)

Specificity and Use

TH / Tyrosine Hydroxylase antibody was raised against rat tyrosine hydroxylase.
C-Terminus
Recognizes an epitope within the catalytically-active C-terminal end-product. This C-terminal product is ~34kD. (This end product is the result of a partial digestion of the rat TH with chymotrypsin.) Species cross-reactivity: Human, primate, mouse.
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:1000-1:2000. Immunohistochemistry: 1:1000 -1:2000 in PBS/0.3% Triton X-100 Cy3 Technique 1:4000-1:8000 in PBS/0.3% Triton X-100 Bn-Av/HRP Technique. Control Tissue: Rat striatum and substantia nigra. Perfusion Fixation: Fixative-4% paraformaldehyde in 0.1 M Phosphate buffer, pH 7.4. Post Fixation-1.5 hr. at 4? C in 4% paraformaldehyde in 0.1 M Phosphate buffer, pH 7.4. Sections: 10um cryostat frozen sections or 50um vibratome sections.

Packaging

Lyophilized.
50 µl or 100 µl deionized water
For research use only.

About TH / Tyrosine Hydroxylase

P07101 NM_000360 NP_000351.2

TH Antibody, DYT14 Antibody, Dystonia 14 Antibody, TYH Antibody, Tyrosine 3-hydroxylase Antibody, Tyrosine hydroxylase Antibody, DYT5b Antibody, Tyrosine 3-monooxygenase Antibody

Tyrosine hydroxylase in involved in the conversion of phenylalanine to dopamine. It is the rate-limiting enzyme in the synthesis of catecholamines and as such has a key role in the physiology of adrenergic neurons. TH is encoded by four distinct mRNAs produced by alternative splicing of a single primary transcript. Expression of the mRNAs varies in different parts of the nervous system. Defects in TH are the cause of autosomal recessive Segawa syndrome.

Requested From: United States
Date Requested: 12/2/2016

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