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TFEB Antibody (C‑Terminus) LS‑C31138
TFEB antibody LS-C31138 is an unconjugated rabbit polyclonal antibody to TFEB from human, mouse, rat and other species. Validated for WB.
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Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot
Product Description
TFEB antibody LS-C31138 is an unconjugated rabbit polyclonal antibody to TFEB from human, mouse, rat and other species. Validated for WB.
About TFEB
Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity.
P19484
NM_007162
NP_009093.1
TFEB Antibody, ALPHATFEB Antibody, BHLHE35 Antibody, T-cell transcription factor EB Antibody, TCFEB Antibody, Transcription factor EB Antibody
Specifications
Target
Human TFEB
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit
(tested or 100% immunogen sequence identity)
Predicted
Goat, Chicken, Zebrafish (at least 90% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein A purified
Modifications
Unmodified
Applications
- Western blot (2.5 µg/ml)
- (applications tested for the base form of this product only)
Immunogen
TFEB antibody was raised against synthetic peptide from C-Terminus of human TFEB (P19484, NP_009093). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Galago, Marmoset, Mouse, Rat, Shrew, Hamster, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig (100%); Goat, Turkey, Chicken, Platypus, Lizard (92%); Salmon (91%); Zebrafish (90%); Orangutan, Xenopus (84%).
Blocking Peptide
LS-E13980 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C31138. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Immunizing peptide used to generate LS-C31138. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Epitope
C-Terminus
Specificity
Human TFEB
Presentation
Lyophilized from PBS with 2% sucrose
Reconstitution
100 µl After adding water, will consist of PBS buffer with 2% sucrose
Storage
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.
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Images
Western blot
A: Marker, B: HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
A: Marker, B: HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
A: Marker, B: HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot
A: Marker, B: HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Requested From:
Date Requested: 6/24/2018
Date Requested: 6/24/2018
