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Anti-TFEB Antibody (C-Terminus) LS-C31138

Catalog	Size	Price
LS-C31138-100	100 µg (1 mg/ml)	Unavailable

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Antibody:	Rabbit Polyclonal (IgG) to Human TFEB
Reactivity:	Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit
Application:	Western blot (applications tested for the base form of this product only)
Format:	Unconjugated

Details

Target:	Human TFEB
Host:	Rabbit
Reactivity:	Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Pig, Rabbit (tested or 100% immunogen sequence identity)
Predicted:	Goat, Chicken, Zebrafish (at least 90% immunogen sequence identity)
Clonality:	IgG Polyclonal
Conjugations:	Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Purification:	Protein A purified
Modifications:	Unmodified

Applications

Approved:

Western blot (2.5 µg/ml)
(applications tested for the base form of this product only)

Specificity and Use

Immunogen:

TFEB antibody was raised against synthetic peptide from C-Terminus of human TFEB (P19484, NP_009093). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Baboon, Monkey, Galago, Marmoset, Mouse, Rat, Shrew, Hamster, Elephant, Panda, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig (100%); Goat, Turkey, Chicken, Platypus, Lizard (92%); Salmon (91%); Zebrafish (90%); Orangutan, Xenopus (84%).

Blocking Peptide:

LS-E13980 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C31138. Useful for pre-absorption and neutralization of the antibody's antigen binding site.

Epitope:

C-Terminus

Specificity:

Human TFEB

Packaging

Presentation:	Lyophilized from PBS with 2% sucrose
Reconstitution:	100 µl After adding water, will consist of PBS buffer with 2% sucrose
Storage:	Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
Restrictions:	For research use only.

About TFEB

Uniprot: P19484 NCBI: NM_007162 NP_009093.1

Synonyms: TFEB Antibody, ALPHATFEB Antibody, BHLHE35 Antibody, T-cell transcription factor EB Antibody, TCFEB Antibody, Transcription factor EB Antibody

Description: Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFE3 or MITF. In association with TFE3, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4+ T-cells and thymus-dependent humoral immunity.

(More About TFEB)

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Technical Help Review

Review This Product

Western blot

A: Marker, B: HepG2 Cell Lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From:
Date Requested: 8/20/2017

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