Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone SPM178] (IgG1,k) to Human TFDP1
Human, Mouse, Rat
IHC - Paraffin, Western blot
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [SPM178]
Protein G purified
IHC - Paraffin (1:50)
Western blot (0.5 - 1 µg/ml)
Specificity and Use
TFDP1 antibody was raised against recombinant corresponding to DP-1.
DP-1. Species cross-reactivity: human, mouse and rat
Immunohistochemistry (formalin fixed paraffin embedded): 1:50 for 30 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min.
PBS, pH 7.4, 0.2% BSA, 0.05% sodium azide
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months.
Can stimulate E2F-dependent transcription. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis.