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Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.
Gene Name: | transcription factor AP-2 delta (activating enhancer binding protein 2 delta) |
Family/Subfamily: | Transcription Factor |
Synonyms: | TFAP2D, AP2-delta, AP-2 like, TFAP2BL1 |
Target Sequences: | NM_172238 NP_758438.2 Q7Z6R9 |
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