Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Human, Rat (at least 90% immunogen sequence identity)
Western blot (1 - 10 µg/ml)
ELISA (0.5 - 1 µg/ml)
Synthetic 15 amino acid peptide sequence mapping in the mid-region of mouse telomerase.
Recognizes mouse FM3A Telomerase at 125kD. Also reacts with human immortal cell line 293. Species sequence Homology: Human and rat, 100%. No significant homology with yeast telomerase.
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml using ECL. Mouse telomerase detected in testes, thymus and spleen. ELISA: 0.5-1 ug/ml. Coat ELISA plates with 1 ug/ml control peptide.
PBS, pH 7.5, 0.1% BSA.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.