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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TERF2 / TRF2 Antibody IHC‑plus™ LS‑B6437
Note: This antibody replaces LS-C832
TRF2 antibody LS-B6437 is an unconjugated goat polyclonal antibody to TRF2 (TERF2) from human and mouse. Validated for ChrIP, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
Catalog
Size
Price
LS-B6437-50
50 µg (0.5 mg/ml)
Unavailable

Popular TERF2 / TRF2 Products

Antibody
Species: Human, Rat
Applications: ICC, Western blot
Transfected 293T cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Xenopus
Applications: Western blot
Anti-TERF2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3851 concentration 3.75 ug/ml.
Species: Human, Monkey, Bat, Bovine, Dog, Horse, Pig
Applications: IHC, IHC - Paraffin
Antibody
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, ELISA, Chromatin Immunoprecipitation

Product Description

TRF2 antibody LS-B6437 is an unconjugated goat polyclonal antibody to TRF2 (TERF2) from human and mouse. Validated for ChrIP, IHC, IP and WB. Tested on 20 paraffin-embedded human tissues.
About TERF2 / TRF2
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Q15554 NM_005652 NP_005643.2

TERF2 Antibody, TRF2 Antibody, TRBF2 Antibody, TTAGGG repeat-binding factor 2 Antibody, Telomeric DNA-binding protein Antibody


Specifications

Target
Human TERF2 / TRF2
Host
Goat
Reactivity
Human, Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (15 µg/ml)
  • Western blot
  • Immunoprecipitation
  • Chromatin Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
TERF2 / TRF2 antibody was raised against recombinant human TERF2.
Specificity
Baculovirus expressed His-tagged whole length TRF2 protein was used for immunizing goat.
Presentation
PBS containing 0.05% BSA and 0.05% sodium azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Immunohistochemistry

Anti-TERF2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6437 concentration 15 ug/ml.
Anti-TERF2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6437 concentration 15 ug/ml.

Western blot

Immunoprecipitation (IP)/ Western blot of TRF2 in HL60 cells. Lane 1. IP with mouse anti-TRF2 antibody. Lane 2. IP with control mouse IgG. Lane 3 IP with goat anti-TRF2 antibody. Lane 4. IP with pre-immune goat Ig. TRF2 is detected as an ~66 kD protein.
Immunoprecipitation (IP)/ Western blot of TRF2 in HL60 cells. Lane 1. IP with mouse anti-TRF2 antibody. Lane 2. IP with control mouse IgG. Lane 3 IP with goat anti-TRF2 antibody. Lane 4. IP with pre-immune goat Ig. TRF2 is detected as an ~66 kD protein.

Immunohistochemistry

Anti-TERF2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6437 concentration 15 ug/ml.
Anti-TERF2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6437 concentration 15 ug/ml.

Western blot

Immunoprecipitation (IP)/ Western blot of TRF2 in HL60 cells. Lane 1. IP with mouse anti-TRF2 antibody. Lane 2. IP with control mouse IgG. Lane 3 IP with goat anti-TRF2 antibody. Lane 4. IP with pre-immune goat Ig. TRF2 is detected as an ~66 kD protein.
Immunoprecipitation (IP)/ Western blot of TRF2 in HL60 cells. Lane 1. IP with mouse anti-TRF2 antibody. Lane 2. IP with control mouse IgG. Lane 3 IP with goat anti-TRF2 antibody. Lane 4. IP with pre-immune goat Ig. TRF2 is detected as an ~66 kD protein.

Immunohistochemistry

Anti-TERF2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6437 concentration 15 ug/ml.
Anti-TERF2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6437 concentration 15 ug/ml.

Western blot

Immunoprecipitation (IP)/ Western blot of TRF2 in HL60 cells. Lane 1. IP with mouse anti-TRF2 antibody. Lane 2. IP with control mouse IgG. Lane 3 IP with goat anti-TRF2 antibody. Lane 4. IP with pre-immune goat Ig. TRF2 is detected as an ~66 kD protein.
Immunoprecipitation (IP)/ Western blot of TRF2 in HL60 cells. Lane 1. IP with mouse anti-TRF2 antibody. Lane 2. IP with control mouse IgG. Lane 3 IP with goat anti-TRF2 antibody. Lane 4. IP with pre-immune goat Ig. TRF2 is detected as an ~66 kD protein.

Immunohistochemistry

Anti-TERF2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6437 concentration 15 ug/ml.
Anti-TERF2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6437 concentration 15 ug/ml.

Western blot

Immunoprecipitation (IP)/ Western blot of TRF2 in HL60 cells. Lane 1. IP with mouse anti-TRF2 antibody. Lane 2. IP with control mouse IgG. Lane 3 IP with goat anti-TRF2 antibody. Lane 4. IP with pre-immune goat Ig. TRF2 is detected as an ~66 kD protein.
Immunoprecipitation (IP)/ Western blot of TRF2 in HL60 cells. Lane 1. IP with mouse anti-TRF2 antibody. Lane 2. IP with control mouse IgG. Lane 3 IP with goat anti-TRF2 antibody. Lane 4. IP with pre-immune goat Ig. TRF2 is detected as an ~66 kD protein.


Requested From: 
Date Requested: 6/25/2018

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