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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TERF2 / TRF2 Antibody LS‑C18052
TRF2 antibody LS-C18052 is an unconjugated mouse monoclonal antibody to TRF2 (TERF2) from human and rat. Validated for ICC and WB.
Antibody
Catalog
Size
Price
LS-C18052-100
100 µg (0.5 mg/ml)
$635

Popular TERF2 / TRF2 Products

Anti-TERF2 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6437 concentration 15 ug/ml.
Species: Human, Mouse
Applications: IHC, IHC - Paraffin, Western blot, Immunoprecipitation, Chromatin Immunoprecipitation
Anti-TERF2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3851 concentration 3.75 ug/ml.
Species: Human, Monkey, Bat, Bovine, Dog, Horse, Pig
Applications: IHC, IHC - Paraffin
Transfected 293T cell lysate. Antibody concentration: 5.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Xenopus
Applications: Western blot
Antibody
Species: Human, Mouse, Rat
Applications: IHC, IHC - Paraffin, IHC - Frozen, ICC, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, ELISA, Chromatin Immunoprecipitation

Product Description

TRF2 antibody LS-C18052 is an unconjugated mouse monoclonal antibody to TRF2 (TERF2) from human and rat. Validated for ICC and WB.
About TERF2 / TRF2
Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Q15554 NM_005652 NP_005643.2

TERF2 Antibody, TRF2 Antibody, TRBF2 Antibody, TTAGGG repeat-binding factor 2 Antibody, Telomeric DNA-binding protein Antibody


Specifications

Target
Human TERF2 / TRF2
Host
Mouse
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ICC
  • Western blot (0.5 - 2 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
TERF2 / TRF2 antibody was raised against his-tagged, fusion-protein, corresponding to full-length TRF2 (TTAGGG Repeat binding Factor 2), expressed in baculovirus.
Specificity
Recognizes TRF2, Mr 66kD. Species cross-reactivity: Human and rat.
Usage
Suitable for use in Western Blot and has been reported to demonstrate cell nuclear staining in Immunocytochemistry. Western Blot: 0.5-2 ug/ml detects TRF2 from a RIPA lysate of human Jurkat cells. TRF2 may be detected as a doublet in some cell lysates. Jurkat cell lysate was resolved by electrophoresis, transferred to nitrocellulose and probed with anti-TRF2 (1 ug/ml). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system.
Presentation
PBS, pH 7.2, 0.05% Sodium Azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: United States
Date Requested: 8/20/2018

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