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Anti-TERF2 / TRF2 Antibody (clone 4A794.15) LS-C606

Ordering

Wt. Vol. Conc. Price
100 µg 200 µl 0.5 mg/ml $335
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
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Mouse Monoclonal [clone 4A794.15] (IgG1,k) to Human TERF2 / TRF2
Human, Mouse, Rat, Deer
IHC - Frozen, ICC, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Unconjugated

Details

Human TERF2 / TRF2
Mouse
Human, Mouse, Rat, Deer (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [4A794.15]
Protein G purified

Applications

IHC - Frozen (5 µg/ml), ICC, Western blot (2 - 4 µg/ml), Immunoprecipitation, Flow Cytometry, ELISA (2 µg/ml)

Specificity and Use

TERF2 / TRF2 antibody was raised against full length TRF2 protein.
The recognizes distinct doublet bands of approximate size 66 kD corresponding to the molecular size of huTRF2 by western blot analysis against lysates from most human cell lines.

Packaging

PBS, 0.05% BSA, 0.05% sodium azide.
Long term: -70°C; Short term: +4°C
For research use only.

About TERF2 / TRF2

Q15554 NM_005652 NP_005643.2

TERF2 Antibody, TRF2 Antibody, TRBF2 Antibody, TTAGGG repeat-binding factor 2 Antibody, Telomeric DNA-binding protein Antibody

Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and plays a central role in telomere maintenance and protection against end-to-end fusion of chromosomes. In addition to its telomeric DNA-binding role, required to recruit a number of factors and enzymes required for telomere protection, including the shelterin complex, TERF2IP/RAP1 and DCLRE1B/Apollo. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection.

Immunocytochemistry

Immunocytochemistry
Immunofluorescent staining of TRF2-bound telomeres in human HeLa cells (Courtesy of Fotiadou, et al, 2004).

Western blot

Western blot
Western blot of TRF2 in human Jurkat cell lysate using TRF2 antibody at 2 ug/ml.

Flow Cytometry

Flow Cytometry
Intracellular flow cytometry of TRF2 in 10^6 human Jurkat cells using 0.1 ug of LS-C606. The shaded histogram represents cells alone, blue represents isotype control and red represents LS-C606, anti-TRF2.
 

Requested From: United States
Date Requested: 9/26/2016

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