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TEAD1

TEA domain family member 1 (SV40 transcriptional enhancer factor)

Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner. The activation function appears to be mediated by a limiting cell-specific transcriptional intermediary factor (TIF). Involved in cardiac development. Binds to the M-CAT motif.

Gene Name: TEA domain family member 1 (SV40 transcriptional enhancer factor)
Synonyms: TEAD1, AA, Protein GT-IIC, TCF-13, TEAD-1, TEF-1, TEF1, TCF13, TEA domain family member 1, Transcription factor 13, NTEF-1, REF1
Target Sequences: NM_021961 NP_068780.2 P28347

Publications (1)

1
RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer. Y Qiao, S J Lin, Y Chen, D C-C Voon, F Zhu, L S H Chuang, T Wang, P Tan, S C Lee, K G Yeoh, M Sudol, Y Ito. Oncogene. 2016 May;35:2664-74. [Full Text Article] [PubMed:26364597]

☰ Filters
Antibodies (24)
Proteins (1)
Primary (24)
Recombinant (1)
TEAD1 (25)
Human (23)
Mouse (17)
Rat (13)
Bat (3)
Bovine (7)
Chicken (4)
Chimpanzee (6)
Dog (7)
Gibbon (9)
Guinea pig (6)
Horse (6)
Monkey (9)
Pig (7)
Rabbit (9)
Xenopus (3)
Zebrafish (4)
IHC (11)
IHC-P (5)
WB (24)
ChrIP (2)
ELISA (5)
ICC (2)
IF (6)
Peptide-ELISA (1)
rabbit (23)
mouse (1)
Product Group
IHCPlus (1)
Ig (1)
IgG (16)
IgG1 (1)
monoclonal mc (1)
polyclonal pc (23)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (15)
C-Terminus (5)
N-Terminus (4)
aa195-244 (4)
30-110 aa, Internal (1)
Internal (1)
aa105-150 (1)
aa135-215 (1)
No (25)
6His, N-terminus (1)
Human (1)
E. coli (1)
Purified (1)
TEAD1 Antibody - Anti-TEAD1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TEAD1 Antibody - Anti-TEAD1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
TEAD1 Antibody - Anti-TEAD1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
TEAD1 Antibody - Anti-TEAD1 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Xenopus, Chicken, Zebrafish, Pig, Horse, Bat, Rat, Bovine, Rabbit, Mouse, Dog, Guinea pig, Human, Monkey, Gibbon, Chimpanzee
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
TEAD1 Antibody - Immunohistochemistry of paraffin-embedded human lung cancer tissue.
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TEAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ChrIP, IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
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TEAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ChrIP, IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
TEAD1 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
TEAD1 Antibody - Immunofluorescent analysis of TEAD1 staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue).
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TEAD1 Rabbit anti-Human Polyclonal (Internal) Antibody
Chicken, Bovine, Mouse, Dog, Rat, Pig, Human
ICC, IF, WB
Unconjugated
100 µl/$299
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TEAD1 Rabbit anti-Human Polyclonal (30-110 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TEAD1 Antibody - TEAD1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (aa195-244) Antibody
Human
WB
Unconjugated
100 µl/$424
TEAD1 Antibody - TEAD1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (aa195-244) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
TEAD1 Antibody - TEAD1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (aa195-244) (Biotin) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
TEAD1 Antibody - TEAD1 antibody Western blot of HeLa lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (aa195-244) (FITC) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Pig, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
TEAD1 Antibody - 1:100 staining mouse pancreas tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TEAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TEAD1 Antibody - Immunohistochemistry of paraffin-embedded human placenta using antibody at 1:100 dilution.
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TEAD1 Rabbit anti-Human Polyclonal (aa135-215) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$294; 100 µl/$360
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TEAD1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$341
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TEAD1 Rabbit anti-Human Polyclonal (aa105-150) Antibody
Mouse, Rat, Human
ICC, IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
TEAD1 Antibody - Immunofluorescence analysis of MCF-7 cells using TEAD1 Polyclonal Antibody.
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TEAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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TEAD1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
TEAD1 Antibody - Zebrafish tead1b Antibody (C-term) western blot analysis in zebrafish heart tissue lysates (35ug/lane).This demonstrates the TEAD1 antibody detected the TEAD1 protein (arrow).
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TEAD1 Rabbit anti-Zebrafish Polyclonal (C-Terminus) Antibody
Zebrafish
ELISA, WB
Unconjugated
400 µl/$393
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TEAD1 Mouse anti-Human Monoclonal Antibody
Human
WB
Unconjugated
50 µg/$558
TEAD1 Antibody - Fetal Muscle Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$397
TEAD1 Antibody - Fetal Muscle Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TEAD1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody
Rabbit, Mouse, Human, Monkey, Gibbon
WB
HRP Conjugated
100 µl/$442
TEAD1 Antibody - Fetal Muscle Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TEAD1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody
Rabbit, Mouse, Human, Monkey, Gibbon
WB
Biotin Conjugated
100 µl/$442
TEAD1 Antibody - Fetal Muscle Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TEAD1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody
Rabbit, Mouse, Human, Monkey, Gibbon
WB
FITC Conjugated
100 µl/$442
Viewing 1-25 of 25 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).