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Anti-TDP-43 / TARDBP Antibody (aa72-121) LS-C80134

Ordering

Wt. Vol. Conc. Price
50 µg 50 µl - $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TDP-43 / TARDBP Antibodies

Anti-TDP-43 / TARDBP Antibody (clone 2E2-D3) IHC-plus™ LS-B4521
Mouse Monoclonal [clone 2E2-D3] (IgG1,k) to Human TDP-43 / TARDBP
Human
IHC - Paraffin, Immunofluorescence, Western blot, ELISA, RNA interference
Unconjugated
Immunohistochemistry Image
Anti-TDP-43 / TARDBP Antibody LS-C124633
Rat Monoclonal (IgG2a,k) to Human TDP-43 / TARDBP
Human
IHC, Western blot, ELISA
Unconjugated
Anti-TDP-43 / TARDBP Antibody (C-Terminus) LS-C144920
Rabbit Polyclonal to Mouse TDP-43 / TARDBP
Mouse
IHC, Western blot
Unconjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human TDP-43 / TARDBP
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human TDP-43 / TARDBP
Rabbit
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Guinea pig, Horse, Pig, Rabbit, Chicken, Zebrafish (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • (applications tested for the base form of this product only)

  • IHC - Paraffin

Specificity and Use

TDP-43 / TARDBP antibody was raised against synthetic peptide located between aa72-121 of human TARDBP (Q13148, NP_031401). Percent identity by BLAST analysis: Human, Chimpanzee, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Platypus (100%); Xenopus (85%).
LS-E12754 - Lyophilized - 100 µg - $145.00
aa72-121
Human TARDBP
ELISA titer using peptide based assay: 1:312500. Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1:50000 - 100000 as second antibody.

Packaging

Lyophilized from PBS with 2% sucrose
50 µl Distilled Water.
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About TDP-43 / TARDBP

Q13148 NM_007375 NP_031401.1

TARDBP Antibody, ALS10 Antibody, TAR DNA-binding protein-43 Antibody, TDP-43 Antibody, TAR DNA binding protein Antibody, TAR DNA-binding protein 43 Antibody, TDP43 Antibody

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division.

Western blot

Western blot
Fetal liver lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/11/2016

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