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Anti-TDP-43 / TARDBP Antibody (aa1-260, clone K1B8) IHC-plus™ LS-B2957

Note: This antibody replaces LS-C93800


Wt. Vol. Conc. Price
50 µg 50 µl 1 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular TDP-43 / TARDBP Antibodies

Anti-TDP-43 / TARDBP Antibody (clone 2E2-D3) IHC-plus™ LS-B4521
Mouse Monoclonal [clone 2E2-D3] (IgG1,k) to Human TDP-43 / TARDBP
IHC - Paraffin, Immunofluorescence, Western blot, ELISA, RNA interference
Immunohistochemistry Image
Anti-TDP-43 / TARDBP Antibody LS-C124633
Rat Monoclonal (IgG2a,k) to Human TDP-43 / TARDBP
IHC, Western blot, ELISA
Anti-TDP-43 / TARDBP Antibody (C-Terminus) LS-C144920
Rabbit Polyclonal to Mouse TDP-43 / TARDBP
IHC, Western blot

100% Guaranteed 100% Guaranteed
Mouse Monoclonal [clone K1B8] (IgG1,k) to Human TDP-43 / TARDBP
IHC - Paraffin, Western blot, ELISA


Human TDP-43 / TARDBP
Human (tested or 100% immunogen sequence identity)
IgG1,k Monoclonal [K1B8]
Protein G purified


  • IHC - Paraffin (10 µg/ml)
  • Western blot (1:1000 - 1:2000)

Specificity and Use

TDP-43 / TARDBP antibody was raised against recombinant human TARDBP (1-260aa) purified from E. coli.
Immunohistochemistry: LS-B2957 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2957 was determined to be 10 ug/ml.


PBS, pH 7.4, 0.1% sodium azide. Sourced in Ascites.
Long term: -20°C; Short term: +4°C; Avoid freeze-thaw cycles.
For research use only.

About TDP-43 / TARDBP

Q13148 NM_007375 NP_031401.1

TARDBP Antibody, ALS10 Antibody, TAR DNA-binding protein-43 Antibody, TDP-43 Antibody, TAR DNA binding protein Antibody, TAR DNA-binding protein 43 Antibody, TDP43 Antibody

DNA and RNA-binding protein which regulates transcription and splicing. Involved in the regulation of CFTR splicing. It promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. May also be involved in microRNA biogenesis, apoptosis and cell division.


Anti-TARDBP antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2957 concentration 10 ug/ml.


Anti-TARDBP antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2957 concentration 10 ug/ml.


Anti-TARDBP antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2957 concentration 10 ug/ml.

Western blot

Western blot
Cell lysates of HeLa(20 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human TARDBP (1:1000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Requested From: United States
Date Requested: 10/21/2016

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