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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TDO2 Antibody (clone 2A4) LS‑C174023
TDO2 antibody LS-C174023 is an unconjugated mouse monoclonal antibody to human TDO2. Validated for IHC and WB. Cited in 1 publication.
Catalog
Size
Price
LS-C174023-100
100 µl (1 mg/ml)
Unavailable

Popular TDO2 Products

TDO2 antibody LS-C111058 Western blot of Fetal Small Intestine lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Mouse, Rat, Bovine, Dog, Guinea pig, Pig, Rabbit, Xenopus
Applications: Western blot
Anti-TDO2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5791 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Monkey, Dog
Applications: IHC, IHC - Paraffin, Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.
Species: Human
Applications: Western blot
Anti-TDO / TPH2 / TDO2 antibody IHC staining of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot

Product Description

TDO2 antibody LS-C174023 is an unconjugated mouse monoclonal antibody to human TDO2. Validated for IHC and WB. Cited in 1 publication.
About TDO2
TDO2 is a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. P48775 NM_005651 NP_005642.1

TDO2 Antibody, TDO Antibody, TO Antibody, TRPO Antibody, Tryptophan pyrrolase Antibody, Tryptophan oxygenase Antibody, Tryptophan 2,3-dioxygenase Antibody, Tryptophanase Antibody, Tryptamin 2,3-dioxygenase Antibody


Specifications

Target
Human TDO2
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal [2A4]
Conjugations
Unconjugated
Purification
Protein A/G purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Paraffin (1:150)
  • Western blot (1:2000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
TDO2 antibody was raised against full length human recombinant protein of human TDO2(NP_005642) produced in HEK293T cell.
Specificity
Human TDO / TDO2
Presentation
PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Storage
Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

Publications (1)

1
Prognostic Significance of Tryptophan Catabolism in Adult T-cell Leukemia/Lymphoma. Masaki A, Ishida T, Maeda Y, Suzuki S, Ito A, Takino H, Ogura H, Totani H, Yoshida T, Kinoshita S, Narita T, Ri M, Kusumoto S, Inagaki A, Komatsu H, Niimi A, Ueda R, Utsunomiya A, Inagaki H, Iida S. Clinical cancer research : an official journal of the American Association for Cancer Research. 2015 21:2830-9. (IHC, IF; Human) [Full Text Article] [PubMed:25788494]

Customer Reviews (0)


Images


Immunohistochemistry

IHC of paraffin-embedded Human pancreas tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human tonsil using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human breast tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human breast tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human liver tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human liver tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human colon tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human colon tissue using anti-TDO2 mouse monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.

Immunohistochemistry

IHC of paraffin-embedded Human pancreas tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human tonsil using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human breast tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human breast tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human liver tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human liver tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human colon tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human colon tissue using anti-TDO2 mouse monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.

Immunohistochemistry

IHC of paraffin-embedded Human pancreas tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human tonsil using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human breast tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human breast tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human liver tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human liver tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human colon tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human colon tissue using anti-TDO2 mouse monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.

Immunohistochemistry

IHC of paraffin-embedded Human pancreas tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human pancreas tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human ovary tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human prostate tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human prostate tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human tonsil using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human tonsil using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human breast tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human breast tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human liver tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human liver tissue using anti-TDO2 mouse monoclonal antibody.

Immunohistochemistry

IHC of paraffin-embedded Human colon tissue using anti-TDO2 mouse monoclonal antibody.
IHC of paraffin-embedded Human colon tissue using anti-TDO2 mouse monoclonal antibody.

Western blot

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.


Requested From: 
Date Requested: 6/23/2018

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