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Anti-TDO2 Antibody (clone 1B1) LS-C173912

Catalog Size Price
LS-C173912-100 100 µl (1 mg/ml) Unavailable

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100% Guaranteed
Mouse Monoclonal [clone 1B1] (IgG1) to Human TDO2
Human
Western blot
Unconjugated

Details

Human TDO2
Mouse
Human (tested or 100% immunogen sequence identity)
IgG1 Monoclonal [1B1]
Unconjugated
Protein A/G purified
Unmodified

Applications

Western blot (1:1000)

Specificity and Use

TDO2 antibody was raised against full length human recombinant protein of human TDO2(NP_005642) produced in HEK293T cell.
Human TDO / TDO2

Packaging

PBS, pH 7.3, 1% BSA, 50% glycerol, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.

About TDO2

P48775 NM_005651 NP_005642.1

TDO2 Antibody, TDO Antibody, TO Antibody, TRPO Antibody, Tryptophan pyrrolase Antibody, Tryptophan oxygenase Antibody, Tryptophan 2,3-dioxygenase Antibody, Tryptophanase Antibody, Tryptamin 2,3-dioxygenase Antibody

TDO2 is a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.

Western blot

Western blot
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY TDO2 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-TDO2.

Requested From: 
Date Requested: 8/17/2017

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