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Anti-TDG / Thymine DNA Glycosylase Antibody (aa31-80) LS-C119026

Ordering

Wt. Vol. Conc. Price
- 20 µl - $205
- 50 µl - $255
- 100 µl - $315
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular TDG / Thymine DNA Glycosylase Antibodies

Anti-TDG / Thymine DNA Glycosylase Antibody LS-C334266
Rabbit Polyclonal (IgG) to Human TDG / Thymine DNA Glycosylase
Human, Mouse, Rat
IHC, Immunofluorescence, Western blot
Unconjugated
Western blot Image
Anti-TDG / Thymine DNA Glycosylase Antibody LS-C335140
Rabbit Polyclonal (IgG) to Human TDG / Thymine DNA Glycosylase
Human, Mouse, Rat
Western blot
Unconjugated
Western blot Image
Anti-TDG / Thymine DNA Glycosylase Antibody (Internal) LS-C354097
Rabbit Polyclonal to Human TDG / Thymine DNA Glycosylase
Human, Mouse, Rat, Bovine
ICC, Immunofluorescence, Western blot
Unconjugated
Immunofluorescence Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human TDG / Thymine DNA Glycosylase
Human, Mouse, Rat
Western blot, ELISA
Unconjugated

Details

Human TDG / Thymine DNA Glycosylase
Rabbit
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • ELISA

Specificity and Use

TDG / Thymine DNA Glycosylase antibody was raised against synthetic peptide from human TDG (aa31-80).
aa31-80
TDG Antibody detects endogenous levels of total TDG protein.

Packaging

PBS (without Mg2+, Ca2+), pH 7.4, 150 mM sodium chloride, 0.02% sodium azide, 50% glycerol
Store at -20°C for up to one year.
For research use only.

About TDG / Thymine DNA Glycosylase

Q13569 NM_003211 NP_003202.3

TDG Antibody, Thymine-DNA glycosylase Antibody, Thymine DNA Glycosylase Antibody

DNA glycosylase that plays a key role in active DNA demethylation: specifically recognizes and binds 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC) in the context of CpG sites and mediates their excision through base-excision repair (BER) to install an unmethylated cytosine. Cannot remove 5-hydroxymethylcytosine (5hmC). According to an alternative model, involved in DNA demethylation by mediating DNA glycolase activity toward 5-hydroxymethyluracil (5hmU) produced by deamination of 5hmC.

Western blot

Western blot
Western blot of extracts from Jurkat cells, using TDG Antibody. The lane on the right is treated with the synthesized peptide.
 

Requested From: United States
Date Requested: 12/8/2016

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