Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone MEM-262] (IgG2a) to Human TCR Vbeta5
Western blot, Immunoprecipitation, Flow Cytometry, Functional Assay
Human TCR Vbeta5
Human (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [MEM-262]
Protein A purified
IHC - Paraffin
Specificity and Use
TCR Vbeta5 antibody was raised against human thymoma cell line HPB-ALL.
Recognizes beta chains of the TCR expressed by HPB-ALL cell line [carrying V(beta5.3)] and a small subset of peripheral blood T cells. This subset is larger than that recognized by other V(beta5.3)-specific antibodies
Western Blotting: Uniquely recognizes denatured TCR beta chains under the conditions of Western blotting. Functional Application: Activates T cells (V beta 5-related subset). The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.
Azide free PBS, preserved by filter sterilization, approx., pH 7.4.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.