Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone G101] (IgG2a) to Rat TCR Vbeta10
Rat TCR Vbeta10
Rat (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [G101]
Ion exchange chromatography
Flow Cytometry (1:50 - 1:100)
IHC - Paraffin
Specificity and Use
TCR Vbeta10 antibody was raised against t cell clone expressing the TCR V beta 10 gene product.
Specific for the T-cell receptor V beta 10 gene product. Approximately 4.2% of unseparated LEW lymph node cells were detected by this clone. Reactivity is restricted to alpha/beta T cells, of which 6.7% labeled.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.
PBS, pH 7.2, 0.09% sodium azide.
Short term 4°C, long term aliquot and store at -20°C, avoid freeze thaw cycles.