Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse, Rat, Bovine, Dog, Hamster, Rabbit, Sheep
(tested or 100% immunogen sequence identity)
Protein G purified
ICC (5 µg/ml)
TCP1 antibody was raised against purified recombinant mouse TCP-1alpha construct encoding the C-terminal half of the 1.8 kb full-length Tcp-1b gene expressed in E. coli.
Recognizes a 60kD protein, corresponding to the apparent molecular mass of TCP-1alpha on SDS-PAGE immunoblots. Species cross-reactivity: Mouse, rat, bovine, sheep, canine, rabbit, hamster and plant.
Suitable for use in Western Blot, Immunoprecipitation and Immunocytochemistry. Western Blot (Colorimetric): 2 ug/ml. Immunoprecipitation (Native): 5 ug/ml Precipitates coatomer and CTT. Immunocytochemistry: 5 ug/ml.
PBS, pH 7.2, 0.09% Sodium Azide, 50% Glycerol
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
TCP1 is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin.