Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TCN2 Antibody, D22S676 Antibody, D22S750 Antibody, Macrocytic anemia Antibody, TC-2 Antibody, TC II Antibody, TCII Antibody, Transcobalamin-2 Antibody, Vitamin B12-binding protein 2 Antibody, Transcobalamin II Antibody, TC Antibody, TC2 Antibody
TCN2 is a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants.
Western Blot analysis of TCN2 expression in transfected 293T cell line by TCN2 monoclonal antibody (M01), clone 2F4.Lane 1: TCN2 transfected lysate (Predicted MW: 47.5 KDa).Lane 2: Non-transfected lysate.
Enzyme-Linked Immunosorbent Assay
Detection limit for recombinant GST tagged TCN2 is 1 ng/ml as a capture antibody.