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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TCF7L2 / TCG4 Antibody (Internal, Biotin) LS‑C142703
TCG4 antibody LS-C142703 is a biotin-conjugated rabbit polyclonal antibody to human TCG4 (TCF7L2). Validated for WB.
Catalog
Size
Price
LS-C142703-100
100 µl
Unavailable

Popular TCF7L2 / TCG4 Products

Antibody
Species: Human, Mouse
Applications: IHC, ICC, Western blot, Immunoprecipitation, ELISA
Antibody
Species: Human, Rat
Applications: Western blot, ELISA
Anti-TCF7L2 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3736 concentration 10 ug/ml.
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Applications: IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Anti-TCF7L2 antibody IHC of human small intestine.
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TCF7L2 Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The TCF7L2 antibody detected the TCF7L2 protein (arrow).
Species: Human, Mouse
Applications: Western blot

Product Description

TCG4 antibody LS-C142703 is a biotin-conjugated rabbit polyclonal antibody to human TCG4 (TCF7L2). Validated for WB.
About TCF7L2 / TCG4
Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Q9NQB0 NM_030756 NP_110383.2

TCF7L2 Antibody, HMG box transcription factor 4 Antibody, HTCF-4 Antibody, T-cell factor-4 variant X2 Antibody, T-cell factor 4 Antibody, Transcription factor 7-like 2 Antibody, TCF-4 Antibody


Specifications

Target
Human TCF7L2 / TCG4
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Biotin. Also available Unconjugated or conjugated with DY650, DY488, DY550.
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (0.5 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
TCF7L2 / TCG4 antibody was raised against synthetic peptide made to an internal portion of the human protein (within residues 150-200). [Swiss-Prot# Q9NQB0]. Percent identity by BLAST analysis: Mouse (93%).
Epitope
Internal
Specificity
TCF7L2.
Usage
The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Presentation
PBS, 0.05% sodium azide
Storage
Store at 4°C. Do not freeze.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

TCF7L2 Antibody - Western Blot on Jurkat cell line.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
TCF7L2 Antibody - Western Blot on Jurkat cell line. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

TCF7L2 Antibody - Western Blot on Jurkat cell line.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
TCF7L2 Antibody - Western Blot on Jurkat cell line. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

TCF7L2 Antibody - Western Blot on Jurkat cell line.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
TCF7L2 Antibody - Western Blot on Jurkat cell line. This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

TCF7L2 Antibody - Western Blot on Jurkat cell line.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
TCF7L2 Antibody - Western Blot on Jurkat cell line. This image was taken for the unconjugated form of this product. Other forms have not been tested.


Requested From: 
Date Requested: 6/19/2018

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