Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
(tested or 100% immunogen sequence identity)
Western blot (1:1000 - 1:10000)
TBX2 antibody was raised against gST fusion protein corresponding to residues 554-702 of human TBX2.
Recognizes TBX2, Mr 74kD. Species cross-reactivity: Human and mouse.
Suitable for use in Western Blot, Immunoprecipitation. Western Blot: 1:1000-1:10000. Detected TBX2 in RIPA A lysates from MCF-7 human breast adenocarcinoma cells. Detection in cells expressing low levels of TBX2 may require Immunoprecipitation prior to immunoblotting.
Serum, 0.05% Sodium Azide
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
TBX2 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent.