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TAOK1 / TAO1

TAO kinase 1

Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade.

Gene Name: TAO kinase 1
Family/Subfamily: Protein Kinase , TAO
Synonyms: TAOK1, MAP3K16, MARK Kinase, HKFC-B, KFC-B, TAO kinase 1, TAO1, MARKK, PSK2, HTAOK1, KIAA1361, Kinase from chicken homolog B, PSK-2, Rat TAO1, STE20-like kinase PSK2, Sulu3
Target Sequences: NM_020791 NP_065842.1 Q7L7X3

☰ Filters
Antibodies (21)
ELISA Kits (3)
Proteins (3)
Custom (3)
Over-Expression Lysate (2)
Primary (21)
Recombinant (1)
TAOK1 / TAO1 (27)
Human (22)
Mouse (8)
Rat (8)
Bat (2)
Bovine (2)
Chicken (1)
Dog (2)
Hamster (2)
Horse (2)
Monkey (3)
Pig (2)
Rabbit (2)
Xenopus (2)
IHC (9)
IHC-P (6)
WB (18)
ELISA (10)
IF (1)
IP (1)
Peptide-ELISA (2)
rabbit (20)
mouse (1)
Product Group
IHCPlus (3)
PathPlus Neuro (1)
IgG (11)
IgG3,k (1)
monoclonal mc (1)
polyclonal pc (20)
4E12 (1)
96-Well Strip Plate (3)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (2)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (13)
Internal (7)
aa620-650 (7)
400-480 aa, Internal (1)
C-Terminus (1)
aa400-450 (1)
aa431-480 (1)
No (27)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (2)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
TAOK1 / TAO1 Antibody - Anti-TAOK1 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
TAOK1 / TAO1 Antibody - Anti-TAOK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Xenopus, Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
TAOK1 / TAO1 Antibody - 1:100 staining mouse brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TAOK1 / TAO1 Antibody - Anti-TAO1 / TAOK1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (aa431-480) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
TAOK1 / TAO1 Antibody - Immunoperoxidase of monoclonal antibody to TAOK1 on formalin-fixed paraffin-embedded human testis. [antibody concentration 3 ug/ml]
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TAOK1 / TAO1 Mouse anti-Human Monoclonal (4E12) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
TAOK1 / TAO1 Antibody - Anti-TAOK1 / TAO1 antibody IHC of human Lung, Non-Small Cell Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (Internal) Antibody
Xenopus, Bat, Rabbit, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (400-480 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
TAOK1 / TAO1 Antibody - Immunohistochemical analysis of TAO1 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (aa620-650) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (aa620-650) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (aa620-650) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (aa620-650) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (aa620-650) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (aa620-650) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (aa400-450) Antibody
Human
IP, WB
Unconjugated
10 µl/$295; 100 µl/$514
TAOK1 / TAO1 Antibody - Western blot of anti-TAOK1 antibody in mouse brain tissue lysate (35 ug/lane). TAOK1(arrow) was detected using the purified antibody.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (aa620-650) Antibody
Human
WB
Unconjugated
400 µl/$393
TAOK1 / TAO1 Antibody - Western blot of TAOK1 Antibody with HepG2 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
WB
Unconjugated
100 µl/$424
TAOK1 / TAO1 Antibody - Western blot of TAOK1 Antibody with HepG2 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (Internal) (HRP) Antibody
Human
WB
HRP Conjugated
100 µl/$469
TAOK1 / TAO1 Antibody - Western blot of TAOK1 Antibody with HepG2 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (Internal) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$469
TAOK1 / TAO1 Antibody - Western blot of TAOK1 Antibody with HepG2 Whole Cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAOK1 / TAO1 Rabbit anti-Human Polyclonal (Internal) (FITC) Antibody
Human
WB
FITC Conjugated
100 µl/$469
TAOK1 / TAO1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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293T Cells
Myc-DDK (Flag)
116.1 kDa
20 µg/$215
TAOK1 / TAO1 ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
TAOK1 / TAO1 ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
Viewing 1-25 of 27 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).