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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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TANK2 / TNKS2 Antibody LS‑C18032
Antibody
TNKS2 antibody LS-C18032 is an unconjugated rabbit polyclonal antibody to human TNKS2 (TANK2). Validated for ELISA and WB.
Catalog
Size
Price
LS-C18032-50
50 µg (1 mg/ml)
Unavailable
LS-C18032-100
100 µg
Unavailable

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Product Description

TNKS2 antibody LS-C18032 is an unconjugated rabbit polyclonal antibody to human TNKS2 (TANK2). Validated for ELISA and WB.
About TANK2 / TNKS2
Poly-ADP-ribosyltransferase involved in various processes such as Wnt signaling pathway, telomere length and vesicle trafficking. Acts as an activator of the Wnt signaling pathway by mediating poly-ADP-ribosylation of AXIN1 and AXIN2, 2 key components of the beta-catenin destruction complex: poly-ADP-ribosylated target proteins are recognized by RNF146, which mediates their ubiquitination and subsequent degradation. Q9H2K2 NM_025235 NP_079511.1

TNKS2 Antibody, PARP-5b Antibody, PARP-5c Antibody, Tankyrase 2 Antibody, Tankyrase-2 Antibody, TNKS-2 Antibody, PARP5B Antibody, PART6 Antibody, Tankyrase-like protein Antibody, Tankyrase-related protein Antibody, ARTD6 Antibody, TNKL Antibody, PARP5C Antibody, TANK2 Antibody, Tankyrase II Antibody


Specifications

Target
Human TANK2 / TNKS2
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Predicted
Rat (at least 90% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • Western blot (1 - 10 µg/ml)
  • ELISA (0.5 - 1 µg/ml)
Immunogen
TANK2 / TNKS2 antibody was raised against a 14-aa Peptide sequence between the ANK15 and SAM domain of human TANK2 (1) was synthesized, coupled to KLH.
Specificity
The human control peptide sequence is not significantly conserved in TANK-1. Antibody cross-reactivity in various species is not established.
Usage
Suitable for use in ELISA and Western Blot. Western Blot: 1-10 ug/ml. Using ECL. TANK1 ~130kD. ELISA: 0.5-1 ug/ml. Control peptide can be used to coat ELISA plates at 1 ug/ml.
Presentation
PBS, pH 7.4, 0.1% BSA, 40% glycerol.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/22/2018

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