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TAGLN / Transgelin / SM22

transgelin

TAGLN / Transgelin / SM22 is a transformation and shape-change sensitive actin cross-linking/gelling protein found in fibroblasts and smooth muscle. Its expression is down-regulated in many cell lines, and this down-regulation may be an early and sensitive marker for the onset of transformation. A functional role of this protein is unclear. Two transcript variants encoding the same protein have been found for this gene.

Gene Name: transgelin
Synonyms: TAGLN, 22 kDa actin-binding protein, SMCC, TAGLN1, WS3-10, Transgelin, Transgelin variant 2, SM22, Protein WS3-10, SM22-alpha
Target Sequences: NM_003186 NP_003177.2 Q01995

Publications (4)

1
Proteomic profiling of chronic low-frequency stimulated fast muscle. Donoghue P, Doran P, Wynne K, Pedersen K, Dunn MJ, Ohlendieck K. Proteomics. 2007 7:3417-30. [PubMed:17708595] Related Antibodies: LS-B2563.
2
Sphingosine 1-phosphate induces differentiation of adipose tissue-derived mesenchymal stem cells towards smooth muscle cells. Nincheri P, Luciani P, Squecco R, Donati C, Bernacchioni C, Borgognoni L, Luciani G, Benvenuti S, Francini F, Bruni P. Cellular and molecular life sciences : CMLS. 2009 66:1741-54. [PubMed:19337690] Related Antibodies: LS-B2563.
3
Transforming growth factor-beta1 induces transdifferentiation of myoblasts into myofibroblasts via up-regulation of sphingosine kinase-1/S1P3 axis. Cencetti F, Bernacchioni C, Nincheri P, Donati C, Bruni P. Molecular biology of the cell. 2010 21:1111-24. [PubMed:20089836] [PMC:PMC2836962] Related Antibodies: LS-B2563.
4
Sphingosine 1-phosphate induces differentiation of mesoangioblasts towards smooth muscle. A role for GATA6. Donati C, Marseglia G, Magi A, Serrat S, Cencetti F, Bernacchioni C, Nannetti G, Benelli M, Brunelli S, Torricelli F, Cossu G, Bruni P. PloS one. 2011 6:e20389. [PubMed:21629665] [PMC:PMC3101247] Related Antibodies: LS-B2563.
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☰ Filters
Antibodies (52)
ELISA Kits (11)
Proteins (11)
Over-Expression Lysate (4)
Primary (52)
Recombinant (7)
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Sandwich CLIA (1)
TAGLN / Transgelin / SM22 (74)
Human (56)
Mouse (17)
Rat (12)
Bat (1)
Bovine (9)
Chicken (1)
Dog (4)
Gibbon (3)
Guinea pig (4)
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Horse (4)
Monkey (5)
Pig (17)
Porcine (1)
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Xenopus (1)
IHC (23)
IHC-P (23)
WB (34)
Flo (7)
ELISA (12)
ICC (2)
IF (13)
IP (1)
Peptide-ELISA (2)
rabbit (38)
mouse (13)
goat (1)
Product Group
IHCPlus (6)
IgG (21)
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IgG1,k (8)
IgG2a,k (2)
monoclonal mc (13)
polyclonal pc (39)
3A3 (1)
4B11 (1)
8C8 (2)
SMP22a (3)
SPM606 (2)
TAGLN/247 (3)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (9)
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Azide-free (3)
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GST, N-terminus (1)
His (1)
His, N-Terminal (1)
Myc-DDK (Flag) (6)
Human (9)
293T Cells (2)
E. coli (3)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (2)
TAGLN / Transgelin / SM22 Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TAGLN / Transgelin / SM22 Goat anti-Human Polyclonal (aa190-201) Antibody
Xenopus, Bat, Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
TAGLN / Transgelin / SM22 Antibody - Anti-TAGLN / SM22 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TAGLN / Transgelin / SM22 Rabbit anti-Rat Polyclonal (C-Terminus) Antibody
Rat, Human
IHC, IHC-P
Unconjugated
100 µl/$485
TAGLN / Transgelin / SM22 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$834
TAGLN / Transgelin / SM22 Antibody - Anti-TAGLN / Transgelin / SM22 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (8C8) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$485
TAGLN / Transgelin / SM22 Antibody - Formalin-fixed and paraffin-embedded human skeletal muscle reacted with TAGLN Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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TAGLN / Transgelin / SM22 Rabbit anti-Human Polyclonal (aa24-51) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
TAGLN / Transgelin / SM22 Protein - Recombinant Transgelin By SDS-PAGE
Select
E. coli
His, N-Terminal
26.3 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
TAGLN / Transgelin / SM22 Antibody - Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TAGLN / Transgelin / SM22 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC-P, WB
Unconjugated
50 µl/$460
TAGLN / Transgelin / SM22 Antibody - Anti-TAGLN / Transgelin / SM22 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (Carrier-free) (8C8) Antibody
Mouse, Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
Select
TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (4B11) Antibody
Human
ELISA
Unconjugated
100 µg/$423
TAGLN / Transgelin / SM22 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with Transgelin antibody (SPM606).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (SPM606) Antibody
Rabbit, Mouse, Bovine, Pig, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
TAGLN / Transgelin / SM22 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with Transgelin antibody (SPM606).  This image was taken for the unmodified form of this product. Other forms have not been tested.
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TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPM606) Antibody
Rabbit, Mouse, Bovine, Pig, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
TAGLN / Transgelin / SM22 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with SM22 antibody (TAGLN/247).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (TAGLN/247) Antibody
Rabbit, Mouse, Bovine, Pig, Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
TAGLN / Transgelin / SM22 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with SM22 antibody (TAGLN/247).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (TAGLN/247) Antibody
Rabbit, Mouse, Bovine, Pig, Human
Flo, IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
TAGLN / Transgelin / SM22 Antibody - Formalin-fixed, paraffin-embedded human colon carcinoma stained with SM22 antibody (TAGLN/247).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (Ready-to-Use) (TAGLN/247) Antibody
Rabbit, Mouse, Bovine, Pig, Human
Flo, IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
Select
TAGLN / Transgelin / SM22 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
TAGLN / Transgelin / SM22 Antibody - Formalin-fixed and paraffin-embedded human skeletal muscle reacted with TAGLN Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Select
TAGLN / Transgelin / SM22 Rabbit anti-Human Polyclonal (aa139-167) Antibody
Mouse, Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
TAGLN / Transgelin / SM22 Antibody - Anti-TAGLN / Transgelin / SM22 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
TAGLN / Transgelin / SM22 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TAGLN / Transgelin / SM22 Antibody - Anti-TAGLN rabbit polyclonal antibody at 1:500 dilution. Lane A: Hela Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 23 kDa. Observed band size: 23 kDa.
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TAGLN / Transgelin / SM22 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
TAGLN / Transgelin / SM22 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) HIER using 10 mM sodium citrate buffer pH 6.
Select
Fast Shipping
TAGLN / Transgelin / SM22 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
ICC, IHC-P
Unconjugated
50 µg/$460
TAGLN / Transgelin / SM22 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
Select
E. coli
GST
49.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
TAGLN / Transgelin / SM22 Protein
Select
E. coli
His
100 µg/$342; 500 µg/$641; 20 µg/$254
TAGLN / Transgelin / SM22 Antibody - IHC testing of FFPE human colon carcinoma with SM22 alpha antibody (clone SMP22a).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (SMP22a) Antibody
Mouse, Human
IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
TAGLN / Transgelin / SM22 Antibody - IHC testing of FFPE human colon carcinoma with SM22 alpha antibody (clone SMP22a).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (Ready-to-Use) (SMP22a) Antibody
Mouse, Human
IF, IHC, IHC-P
Unconjugated, Ready-to-Use
7 ml/$574
TAGLN / Transgelin / SM22 Antibody - IHC testing of FFPE human colon carcinoma with SM22 alpha antibody (clone SMP22a).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
TAGLN / Transgelin / SM22 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SMP22a) Antibody
Mouse, Human
IF, IHC, IHC-P
Unconjugated, Azide-free, BSA-free
100 µg/$574
Viewing 1-25 of 74 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).