Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
TAF15 is a member of the TET family of RNA-binding proteins. The encoded protein plays a role in RNA polymerase II gene transcription as a component of a distinct subset of multi-subunit transcription initiation factor TFIID complexes. Translocations involving this gene play a role in acute leukemia and extraskeletal myxoid chondrosarcoma, and mutations in this gene may play a role in amyotrophic lateral sclerosis.
Immunofluorescence: TAF15 Antibody (4D71) - HeLa cell cultures stained with TAF15 antibody (green) and chicken antibody to vimentin (red). The TAF15 antibody reveals a granular nuclear localization typical of many RNA associated proteins. Blue is a DNA stain.
Western blot of crude HeLa cell homogenate blotted with antibody. This TAF15 (4D71) monoclonal binds strongly and cleanly to a band at about 68 kDa.