Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Mouse Monoclonal [clone VU-1D9] (IgG1) to Human TACSTD1 / EPCAM
IHC - Paraffin, Western blot, Flow Cytometry, ELISA
Rat Monoclonal [clone G8.8] (IgG2a) to Mouse TACSTD1 / EPCAM
Mouse TACSTD1 / EPCAM
Mouse (tested or 100% immunogen sequence identity)
IgG2a Monoclonal [G8.8]
Specificity and Use
TACSTD1 / EPCAM antibody was raised against tE-71 thymic epithelial cell line
The G8.8 monoclonal antibody reacts with the 40 kD mouse EpCAM.
This G8.8 antibody has been tested by flow cytometric analysis of the TE-71 cell line. This can be used at less than or equal to 0.125 ug per test. A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
Aqueous buffer, 0.09% sodium azide, contains stabilizer if necessary
Store at +4°C. Do not freeze. Product is photosensitive and should be protected from light.
May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E.
Staining of the TE-71 cell line with 0.06 ug of APC Rat IgG2a isotype control (blue histogram) or 0.06 ug of APC anti-mouse EpCAM (epithelial cell marker) (purple histogram). Total viable cells were used for analysis. This image was taken for the unconjugated form of this product. Other forms have not been tested.