Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Western blot (1:1000)
Specificity and Use
TACR1 / NK1R antibody was raised against synthetic peptide corresponding to human NK-1 (KLH). Cellular localization: Cell membrane.
Recognizes human NK-1. Species cross-reactivity: rat.
Suitable for use in Western Blot and Immunohistochemistry. Western Blot: 1:1000 (ECL) A band is seen at approximately 53kD representing human NK-1. The actual molecular weight may vary depending on the tissue used. Positive control: SF9 whole cell membrane extracts.
Tachykinin Receptor 1, a member of the Tachykinin Receptor subfamily, is involved in the mediation of phosphatidylinositol metabolism by the tachykinin substance P, also referred to as neurokinin 1. It is associated with the management of depression, anxiety, and stress. It is also involved in regulating behavioral responses, neuronal survival, and cardiovascular and respiratory functions. The tachykinin receptor 1 is implicated in the progression of rheumatoid arthritis and osteoarthritis.