Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat, Human, Monkey, Mouse, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit, Sheep
Rat TAC1 / Substance P
Rat, Human, Monkey, Mouse, Bat, Bovine, Dog, Guinea pig, Hamster, Horse, Rabbit, Sheep (tested or 100% immunogen sequence identity)
Chicken (at least 90% immunogen sequence identity)
Specificity and Use
TAC1 / Substance P antibody was raised against c-RPKPQQFFGLM, corresponding to residues 1-11 of rat Substance P. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Sheep, Hamster, Elephant, Panda, Porcine, Dog, Bat, Bovine, Rabbit, Horse, Platypus, Guinea pig (100%); Turkey, Chicken (91%).
Human, Rat and Mouse
Antiserum, 0.05% sodium azide
Store at -20°C. Aliquot to avoid freeze/thaw cycles.
TAC1 / Substance P is four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Substance P is an antimicrobial peptide with antibacterial and antifungal properties.