Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal (IgG2b) to Rat T Lymphocyte Marker RT 6.1
Rat T Lymphocyte Marker RT 6.1
Rat (tested or 100% immunogen sequence identity)
Tissue culture supernatant
Specificity and Use
PVG lymphoid cells.
Reacts with the Pta. A2 antigen which is present on the majority of peripheral T cells but only expressed at low levels in the thymus (probably by medullary thymocytes). The alloantigen is also known as Ag-F1, ART-2, RT-ly-2 and RT6 agreed at the 4th International Workshop on Alloantigenic Systems in the Rat, 1982. Positive on PVG, PVG-RT1a (DA), PVG-RT11 (AGUS), PVG-RT1u (AO) and PVG-R1-Negative on PVG-PtaDA rats.
Flow Cytometry: Neat-1:10.
0.2 M Tris HCl, pH 7.4, 5-10% fetal calf serum, 0.09% sodium azide.