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SYT1 / Synaptotagmin
synaptotagmin I
May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca2+-dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca2+-independent manner; these are neurexins, syntaxin and AP2.
| Gene Name: | synaptotagmin I |
| Family/Subfamily: | Synaptotagmin , Not assigned-Other |
| Synonyms: | SYT1, SYT, SVP65, Synaptotagmin, Synaptotagmin 1, SytI, Synaptotagmin I, Synaptotagmin-1 |
| Target Sequences: | NM_005639 NP_005630.1 P21579 |
Publications (2)
1
Eyes shut homolog (EYS) interacts with matriglycan of O-mannosyl glycans whose deficiency results in EYS mislocalization and degeneration of photoreceptors. Yu Liu , Miao Yu , Xuanze Shang, My Hong Hoai Nguyen, Shanmuganathan Balakrishnan, Rachel Sager, Huaiyu Hu. Scientific reports. 2020 May;10:7795. [Full Text Article]
[PubMed:32385361]
[PMC:PMC7210881]
Related Antibodies: LS-B5899.
2
16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis. Danielle L Tomasello, Jiyoon L Kim, Yara Khodour, Jasmine M McCammon, Maya Mitalipova, Rudolf Jaenisch, Anthony H Futerman, Hazel Sive. iScience. 2022 January;25:103551. [Full Text Article]
[PubMed:34984324]
[PMC:PMC8693007]
Related Antibodies: LS-B12889.
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SYT1 / Synaptotagmin Goat anti-Human Polyclonal (aa261-273) Antibody
Chicken, Zebrafish, Pig, Horse, Bat, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
SYT1 / Synaptotagmin Mouse anti-Rat Monoclonal Antibody
Xenopus, Chicken, Bovine, Rat, Rabbit, Mouse
IHC, WB
Unconjugated
50 µg/$593; 200 µg/$1,015
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
SYT1 / Synaptotagmin Mouse anti-Human Monoclonal (1A6) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Cancer
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal Antibody
Mouse, Bovine, Rat, Human
ICC, IF, IHC-P, WB
Unconjugated
50 µl/$460
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal (pSer309) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SYT1 / Synaptotagmin Mouse anti-Rat Monoclonal Antibody
Frog, Chicken, Bovine, Rat, Rabbit, Mouse
ICC, IHC, IP, WB
Unconjugated
200 µg/$973
SYT1 / Synaptotagmin Mouse anti-Rat Monoclonal (APC) Antibody
Frog, Chicken, Shark, Bovine, Rat, Rabbit, Mouse
ICC, IHC, IP, WB
APC Conjugated
100 µl/$1,177
SYT1 / Synaptotagmin Mouse anti-Rat Monoclonal (PE) Antibody
Frog, Chicken, Shark, Bovine, Rat, Rabbit, Mouse
ICC, IHC, IP, WB
PE Conjugated
100 µl/$1,177
SYT1 / Synaptotagmin Mouse anti-Rat Monoclonal (ASV48) Antibody
Shark, Rat, Mouse, Monkey
ICC, IHC, IP, WB
Unconjugated
200 µg/$611
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal (DY488) Antibody
Human
Flo
DY488 Conjugated
100 µg/$571
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal (pThr202) Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal (aa136-422) Antibody
Mouse, Rat, Pig, Human
IHC-P, WB
Unconjugated
50 µl/$460
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$341
SYT1 / Synaptotagmin Mouse anti-Rat Monoclonal Antibody
Mouse, Bovine, Rat, Monkey
ICC, IHC, IP, WB
Unconjugated
50 µg/$618; 200 µg/$1,017
Human SYT1 / Synaptotagmin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81465
293T Cells
Myc-DDK (Flag)
47.4 kDa
20 µg/$150
E. coli
His-T7
36.6 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, IHC-P, WB
Unconjugated
100 µg/$575
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal (pThr202) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SYT1 / Synaptotagmin Rabbit anti-Human Polyclonal (pSer309) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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